Please use this identifier to cite or link to this item:
10.1007/s10787-022-00925-z
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DC Field | Value | Language |
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dc.contributor.author | Skesters, A. | - |
dc.contributor.author | Kustovs, D. | - |
dc.contributor.author | Lece, A. | - |
dc.contributor.author | Moreino, E. | - |
dc.contributor.author | Petrosina, E. | - |
dc.contributor.author | Rainsford, K. D. | - |
dc.date.accessioned | 2022-08-16T21:03:02Z | - |
dc.date.available | 2022-08-16T21:03:02Z | - |
dc.date.issued | 2022-04 | - |
dc.identifier.citation | Skesters , A , Kustovs , D , Lece , A , Moreino , E , Petrosina , E & Rainsford , K D 2022 , ' Selenium, selenoprotein P, and oxidative stress levels in SARS-CoV-2 patients during illness and recovery ' , Inflammopharmacology , vol. 30 , no. 2 , pp. 499-503 . https://doi.org/10.1007/s10787-022-00925-z | - |
dc.identifier.issn | 0925-4692 | - |
dc.identifier.uri | https://dspace.rsu.lv/jspui/handle/123456789/9410 | - |
dc.description | Publisher Copyright: © 2022, The Author(s). | - |
dc.description.abstract | Background: This study aimed to assess tendency of oxidative stress in COVID-19 patients depending on severity. Methods: The study was conducted with 80 post-COVID-19 disease patients and 40 acutely ill patients. Content of selenium in blood plasma was detected by a fluorimetric method with di-amino-naphthalene using acidic hydrolysis. Selenoprotein P, malondialdehyde and 4-hydroxynonenal and their metabolite adducts were evaluated by spectrophotometric methods using commercial assay kits. Results: Obtained results showed that selenium content in blood for post-COVID-19 disease patients was of a similar lower norm for Latvian inhabitants. Selenium and seleno-protein P contents for acute patients were significantly decreased compared with post-COVID-19 disease patients. Conclusion: In conclusion, COVID-19 involves induction of antioxidant systems—in case of severe disease, patients have significantly low concentration of selenium, seleno-protein P and higher level of oxidative stress, which, in turn, confirms the more intense formation of free radicals in the body. | en |
dc.format.extent | 5 | - |
dc.format.extent | 516001 | - |
dc.language.iso | eng | - |
dc.relation.ispartof | Inflammopharmacology | - |
dc.rights | info:eu-repo/semantics/openAccess | - |
dc.subject | COVID-19 | - |
dc.subject | Free radicals | - |
dc.subject | Oxidative stress | - |
dc.subject | Selenium | - |
dc.subject | Selenoprotein P | - |
dc.subject | 3.1 Basic medicine | - |
dc.subject | 1.4 Chemical sciences | - |
dc.subject | 1.1. Scientific article indexed in Web of Science and/or Scopus database | - |
dc.subject | Immunology | - |
dc.subject | Pharmacology | - |
dc.subject | Pharmacology (medical) | - |
dc.title | Selenium, selenoprotein P, and oxidative stress levels in SARS-CoV-2 patients during illness and recovery | en |
dc.type | /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article | - |
dc.identifier.doi | 10.1007/s10787-022-00925-z | - |
dc.contributor.institution | Scientific Laboratory of Biochemistry | - |
dc.contributor.institution | Statistics Unit | - |
dc.identifier.url | http://www.scopus.com/inward/record.url?scp=85124468892&partnerID=8YFLogxK | - |
dc.description.status | Peer reviewed | - |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
File | Size | Format | |
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Skesters2022_Article_SeleniumSelenoproteinPAndOxida.pdf | 503.91 kB | Adobe PDF | View/Open |
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