RSU e-resource repository
Rīga Stradiņš University institutional open access e-resource repository on DSpace platform stores different types of digital and digitized materials created by RSU:
- the results of scientific and academic activities (articles and monographs)
- didactic and informative materials
- doctoral theses and students' final theses
- conference materials
- other resources
Instruction to access doctoral theses and students' final theses
Communities in DSpace
Select a community to browse its collections.
- RSU zinātniskais izdevums
- «
- 1 (current)
- 2
- 3
- »
Recent Submissions
Transperineāla priekšdziedzera biopsija: Glīsona pakāpju summu salīdzinājums klīniski nozīmīga priekšdziedzera vēža noteikšanā
(Rīga Stradiņš University, 2024) Riekstiņš, Reinis; Lietuvietis, Vilnis; Faculty of Residency; Rezidentūras studiju fakultāte
Introduction: Prostate cancer (PCa) is the most diagnosed cancer in men. To ensure effective treatment, early and accurate diagnosis is crucial. Multiparametric magnetic resonance imaging (mpMRI) followed by transperineal (TP) prostate biopsy is currently recognized as an early diagnostic method for PCa, significantly improving the detection of clinically significant PCa. Morphological changes in cell architecture in biopsy samples are characterized by the Gleason Score (GS). The GS determined from biopsies can be compared with the GS obtained from full prostate histological examination after radical prostatectomy (RP). It has been shown that GS is a prognostic factor for disease outcomes and recurrence risk, making the GS analysis between biopsy and surgical tissue samples valuable for assessing biopsy quality. Methodology: In a retrospective study, 148 patients underwent both targeted and systematic transperineal biopsies and radical prostatectomy. All patients underwent mpMRI before biopsy, and changes observed during the examination were classified using the PI-RADS system. GS values were compared between biopsy and prostatectomy tissue samples. Data analysis was performed using SPSS software (IBM SPSS v23.0, Armonk, NY: IBM Corp.). A significance level of p<0.05 was used for statistical tests. Results: The combined biopsy approach (targeted + systematic) detected PCa in 56.08% of cases, compared to 40.54% with targeted biopsies alone and 3.38% with systematic biopsies alone. Targeted biopsies were most effective in identifying clinically significant cancer. Analysis and comparison of RP data with biopsy results revealed that GS matched in 52.03% of cases, while 28.38% showed clinically significant increases. Conclusions: The results indicate that GS concordance between biopsy and surgical samples was observed in more than half of the patients in the study population. Clinically significant GS increases were found in one-third of patients. The study results suggest that TP biopsy quality in the study group is adequate for patient selection for surgical treatment based on biopsy results. Further data analysis is needed to evaluate the early diagnostic process for prostate cancer and the impact of individual stages on GS differences between biopsy and surgical tissue samples.
Augšžokļa transversālās dimensijas saistība ar kanīnu impakciju
(Rīga Stradiņš University, 2024) Ozola, Ieva; Jākobsone, Gundega; Faculty of Residency; Rezidentūras studiju fakultāte
Introduction: the aim of the study was to compare the transverse dimension of an individual's maxilla on the side of the impacted canine and on the opposite side without canine impaction, using cone-beam computed tomography (CBCT). Materials and methods: a total of 104 CBCT images of patients with unilaterally impacted maxillary canines (79 palatally impacted and 25 buccally impacted) were analyzed. Maxillary transverse dimension measurements were performed at the dental, alveolar, basal, and nasal levels at both the first premolar and the first molar on both sides of the maxilla, using 3D Slicer software. Differences between the side with the impacted canine and the side without impaction were assessed using paired-samples t-tests. Correlations between variables were assessed using Spearman's correlation test with additional linear regression analysis. Results: statistically significant differences were observed in premolar alveolar width (0,35 mm, p = 0,029) and basal width (0,47 mm, p = 0,021), regardless of the impacted canine position, with the canine impaction side being narrower. In palatal canine impaction group, the premolar basal width on the impaction side was significantly reduced by an average of 0,4 mm (p = 0,027). No significant differences were found in the buccal impaction group as well as between the widths of palatally and buccally impacted canines. In females, the premolar alveolar width, whereas in males, the premolar basal width was significantly reduced on the impaction side (by an average of 0,38 mm, p = 0,019 and 1,03 mm, p = 0,004, respectively). In males, age was positively correlated with premolar dental width (r = 0,504, p = 0,005), molar dental width (r = 0,533, p = 0,004), premolar alveolar width (r = 0,441, p = 0,015) and molar alveolar width (r = 0,481, p = 0,011) differences - with each year of life, the difference in premolar dental width increases by 0,041 mm (p = 0,037), the difference in molar dental width by 0,045 mm (p = 0,028) and the difference in premolar alveolar width by 0,118 mm (p = 0,003) .Conclusions: canine impaction is associated with a local narrowing of the maxilla in the premolar region, which is influenced by gender and age.
Smaga akūta pankreatīta (pankreonekrozes) etioloģija, diagnostika, slimības gaita, ārstēšanas taktika, un iznākums pēdējo 5 gadu laika Daugavpils Reģionālajā slimnīcā
(Rīga Stradiņš University, 2024) Avelidi, Marija Darja; Lovčinovskis, Viktors; Faculty of Residency; Rezidentūras studiju fakultāte
Acute pancreatitis is a pancreatic inflamation that occurs in a short period of time. The pancreas is a small organ located behind the stomach near the duodenum and is involved in digestion. Pancreatitis is most often manifested by pain in the epigastrium. Most of the time ~80% resolve easily without any complications, but severe cases require a multidisciplinary approach. Acute pancreatitis is one of the most actual problems in modern medicine because it is common, ~20%-25% progress with the complication like pancreonecrosis. If acute pancreatitis is untreated can lead to serious health problems such as chronic pain or progress to a chronic form, sometimes with fatal outcome. The aim of this study is to find out how often pancreonecrosis develops compared to all acute pancreatitis, to find out the more common factors that lead to the development of pancreonecrosis, to find out the more common treatment outcome in patients after diagnosis of pancreonecrosis, and to find out the association of mortality with age, sex, aetiological factor, and location of pancreonecrosis. Patient history analysis will be used to investigate this question. Data will be structured and processed in MS Excel 2007 and SPSS 30. In total, 554 people with SSK10 diagnosis code K85 - acute pancreatitis were hospitalized in Daugavpils Regional Hospital in the last 5 years from 2019 to 2023, of which 84 people were diagnosed with acute pancreatitis with pancreonecrosis, 28 women (33.3%) and 56 men (66.7%). The highest number of patients is hospitalised in 2019 - 123 people and the lowest in 2021 - 93 people. On the other hand, the highest number of pancreonecrosis is in 2019 - 23 people or 18.69%, and the lowest number in 2020 - 13 people or 10.83%. The results show that the lethal outcome for pancreonecrosis was 15 patients or 17.9%, which is 2.7% of all pancreatitis cases. The mean age of the patients was 53.3 ± 15.7 years. In general, the predominant aetiological factor for the development of pancreonecrosis during the 5-year follow-up was excessive alcohol consumption in 38 patients (45.2%) and gallstone disease in 26 patients (31%).
Temporomandibulārās locītavas patoloģijas ārstēšanas nepieciešamība Rīgas Stradiņa universitātes Stomatoloģijas institūta studentu klīnikas pacientiem
(Rīga Stradiņš University, 2024) Blumfelde, Līva; Blumfelde, Līva; Faculty of Residency; Rezidentūras studiju fakultāte
Dysfunctions of the temporomandibular joint and tissues associated with its functioning are the most common causes of chronic pain in the orofacial region. Their diagnostics and treatment are complex and require in-depth knowledge of human anatomy, physiology, and psychology. Globally, the treatment of these conditions is receiving increasing attention, and research is being conducted to test the effectiveness of various methods. Aim: This research work aimed to find out how often temporomandibular disorders occur among the Latvian population, using as a research group patients who visit the student clinic of the Institute of Stomatology of Rīga Stradiņš University. Methodology: The INfORM DC/ TMD pain screener questionnaire was translated, and demographic questions were added. Adult patients who visited the RSU SI student clinic from 15.04.2024 to 22.05.2024 were surveyed. The data was collected in Microsoft Office Excel and processed using SPSS statistics software. Results: A total of 201 respondents participated in the study, from which respondents who did not suffer from toothache at the time of filling out the questionnaire were selected for analysis (178). Data from the study indicated that 16.85% of respondents scored at least three points in the TMD pain screener, suggesting a potentially painful TMD. No statistically significant differences were found between the prevalence of TMD among women and men. No relationship was observed between the development of painful TMDs and the age, income, marital status, and educational attainment of respondents. The highest percentage of respondents with painful TMD lived in the capital of the Republic of Latvia, Riga. Conclusions: According to DC/TMD, the prevalence of TMD in the study group was lower than the European average (29%). Further research is necessary to ascertain whether these results correspond to the indicators in the Latvian population.
Krūts barošana, tās ietekme uz augšanas attīstību un svaru pirmsskolas vecuma posmā
(Rīga Stradiņš University, 2024) Breiha, Dagnija; Šmitiņa, Anda; Faculty of Residency; Rezidentūras studiju fakultāte
Background. Breastfeeding is providing lots of benefits for infant and mother, and human milk is known as an optimal source of nutritients for newborn in the first months of life. There are numerous studies that shows positive effect of breastfeeding on physical and cognitive development of a child, including reduced risk of childhood obesity even after breastfeeding has been ceased. Nevertheless, breastfeeding rates don’t reach a target set by World Health Organization, with rates being lower in high income countries. Objective: Objective of this study was to investigate the association between breastfeeding duration and child body mass, height and body mass index. Methods: For a retrospective study medical records of 123 children were selected, data about body mass and height at age of 12 months, 3, 5 and 7 years were retrieved. Statistical methods were used to compare group of children who were breastfed less than three months with those who were breastfed for longer. Results: 85,4% of children were breastfed for 3 months, 70,7% for 6 months, and 47% were breastfed for 12 months. Breastfeeding for less than 3 month is asssociated with increased body mass and height at all ages, but statistically significant association is seen with body mass at 12 month age. Mean weight of children who were breastfed less than three months is 10,79(±1,34) kg, three months breastfed 9,81(±1,05), six months brestfed 9,81(±1,08)kg and nine months brestfed 9,73(±1,06) kg. Obesity rate in all ages is higher for those who were breastfed for less than 3 months- 11,1% versus 3,8% at age of three, 5,6% versus 2,9% at age of five and 16,7% versus 4,8% at age of seven. Conclusion: Study shows association between early cesation of breastfeeding and higher body mass in the first year of life, but there is no relation between breastfeeding and body mass index. Breastfeeding for at least 3 months reduce the risk of obesity at preschool age.