Please use this identifier to cite or link to this item:
10.3390/plants11060819
Title: | Wild-Grown and Cultivated Glechoma hederacea L. : Chemical Composition and Potential for Cultivation in Organic Farming Conditions |
Authors: | Sile, Inga Krizhanovska, Valerija Nakurte, Ilva Mezaka, Ieva Kalane, Laura Filipovs, Jevgenijs Vecvanags, Alekss Pugovics, Osvalds Grinberga, Solveiga Dambrova, Maija Kronberga, Arta Department of Applied Pharmacy Department of Pharmaceutical Chemistry |
Keywords: | Chemical composition;Cultivation;Essential oils;Glechoma hederacea;Harvesting period;1.6 Biological sciences;3.1 Basic medicine;1.1. Scientific article indexed in Web of Science and/or Scopus database |
Issue Date: | 1-Mar-2022 |
Citation: | Sile , I , Krizhanovska , V , Nakurte , I , Mezaka , I , Kalane , L , Filipovs , J , Vecvanags , A , Pugovics , O , Grinberga , S , Dambrova , M & Kronberga , A 2022 , ' Wild-Grown and Cultivated Glechoma hederacea L. Chemical Composition and Potential for Cultivation in Organic Farming Conditions ' , Plants , vol. 11 , no. 6 , 819 . https://doi.org/10.3390/plants11060819 |
Abstract: | Glechoma hederacea L. is a medicinal plant that is known in traditional medicine for its anti-inflammatory, antibacterial, antiviral, and anticancer properties. This study evaluated the potential for commercial production of G. hederacea and compared the chemical composition and activity of 70% ethanol extracts and steam-distilled essential oils from wild-grown and cultivated G. hederacea collected in different harvesting periods. The main compounds identified in the 70% ethanol extracts were phenolic acids (chlorogenic and rosmarinic acids) and flavonoid O-glycosides. The essential oil varied in the three accessions in the range of 0.32-2.98 mL/kg -1 of dry weight. The extracts possessed potent antioxidant and anti-inflammatory properties in LPS-treated bone-marrow-derived macrophages. The results of flow cytometry show that extracts from different vegetation periods reduced the conversion of macrophages to the proinflammatory phenotype M1. The chemical composition varied the most with the different harvesting periods, and the most suitable periods were the flowering and vegetative phases for the polyphenolic compounds and essential oils, respectively. G. hederacea can be successfully grown under organic farming conditions, and cultivation does not significantly affect the chemical composition and biological activity compared to wild-grown plants. |
Description: | Funding Information: Funding: This work was supported by the European Regional Development Fund project “Innovative solutions for growing technologies and applications of spring medicinal and aromatic plants” (Nr. 1.1.1.1/18/A/043). Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. |
DOI: | 10.3390/plants11060819 |
ISSN: | 2223-7747 |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
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Wild_Grown_and_Cultivated_Glechoma_hederacea_L..pdf | 3.05 MB | Adobe PDF | View/Open |
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