Please use this identifier to cite or link to this item:
10.3389/fpsyt.2021.770234
Title: | Dosing Cariprazine Within and Beyond Clinical Trials : Recommendations for the Treatment of Schizophrenia |
Authors: | Rancans, Elmars Dombi, Zsófia Borbála Barabássy, Ágota Department of Psychiatry and Narcology |
Keywords: | antipsychotic;cariprazine;dosing;psychopharmacotherapy;schizophrenia;3.2 Clinical medicine;1.1. Scientific article indexed in Web of Science and/or Scopus database;Psychiatry and Mental health;SDG 3 - Good Health and Well-being |
Issue Date: | 5-Jan-2022 |
Citation: | Rancans , E , Dombi , Z B & Barabássy , Á 2022 , ' Dosing Cariprazine Within and Beyond Clinical Trials : Recommendations for the Treatment of Schizophrenia ' , Frontiers in Psychiatry , vol. 12 , 770234 , pp. 770234 . https://doi.org/10.3389/fpsyt.2021.770234 |
Abstract: | Although the optimal dosing of an antipsychotic medication is known to be essential in the long-term management of schizophrenia, in case of novel drugs such as cariprazine, determining the right dosing strategy is not that simple. Without decades of experience with a particular compound, evidence regarding dosing and titration comes primarily from double-blind, placebo controlled clinical trials that are not necessarily mirroring the real-life experiences of doctors. Via summarizing data from both clinical data (n = 3275) and real-world evidence (observational study n = 116, case studies n = 29), this perspective paper aims to shed a light on the appropriate dosing strategies of cariprazine from treatment initiation through switching strategies to concomitant medications. |
Description: | Publisher Copyright: Copyright © 2022 Rancans, Dombi and Barabássy. |
DOI: | 10.3389/fpsyt.2021.770234 |
ISSN: | 1664-0640 |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
File | Size | Format | |
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Dosing_Cariprazine_Within_and_Beyond_Clinical_Trials.pdf | 391.06 kB | Adobe PDF | View/Open |
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