Please use this identifier to cite or link to this item: 10.22336/rjo.2021.44
Title: Less is more : new one-step intracameral chemotherapy technique
Authors: Borroni, Davide
Bonzano, Chiara
Rachwani-Anil, Rahul
Rocha-de Lossada, Carlos
Martín, Francisco Zamorano
Garcia-Lorente, Maria
Bonzano, Elisabetta
Khaqan, Hussain Ahmad
Department of Doctoral Studies
Keywords: Antineoplastic Agents, Alkylating/therapeutic use;Humans;Infant;Melphalan;Retinal Neoplasms;Retinoblastoma;Retrospective Studies;3.2 Clinical medicine;1.1. Scientific article indexed in Web of Science and/or Scopus database
Issue Date: 2021
Citation: Borroni , D , Bonzano , C , Rachwani-Anil , R , Rocha-de Lossada , C , Martín , F Z , Garcia-Lorente , M , Bonzano , E & Khaqan , H A 2021 , ' Less is more : new one-step intracameral chemotherapy technique ' , Romanian journal of ophthalmology , vol. 65 , no. 3 , pp. 218-221 . https://doi.org/10.22336/rjo.2021.44
Abstract: Purpose: To describe the feasibility of a new one-step approach to aspirate the aqueous and apply melphalan in a single-go without repeated entries into the anterior chamber. Methods: This retrospective non-comparative study was conducted at a referral center and included 12 patients. The one-step approach is described in a step-wise manner. No complications were observed among the patients. Results: One single injection of intracameral melphalan proved to be a successful treatment in nine cases. Two patients required a second injection, which was administered two weeks after the first one following the same technique. Conclusions: This proved to be a reasonable technique for the smooth application of melphalan in the anterior chamber studded with retinoblastoma seeds. Our outcomes revealed that it is an effective, quick, and cost-effective technique. Longer-term data collection is underway, though initial findings are encouraging.
Description: © The Authors.Romanian Society of Ophthalmology.
DOI: 10.22336/rjo.2021.44
ISSN: 2457-4325
Appears in Collections:Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure

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