Less is more : new one-step intracameral chemotherapy technique

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dc.contributor.authorBorroni, Davide
dc.contributor.authorBonzano, Chiara
dc.contributor.authorRachwani-Anil, Rahul
dc.contributor.authorRocha-de Lossada, Carlos
dc.contributor.authorMartín, Francisco Zamorano
dc.contributor.authorGarcia-Lorente, Maria
dc.contributor.authorBonzano, Elisabetta
dc.contributor.authorKhaqan, Hussain Ahmad
dc.contributor.institutionDepartment of Doctoral Studies
dc.date.accessioned2022-02-22T11:45:01Z
dc.date.available2022-02-22T11:45:01Z
dc.date.issued2021
dc.description© The Authors.Romanian Society of Ophthalmology.
dc.description.abstractPurpose: To describe the feasibility of a new one-step approach to aspirate the aqueous and apply melphalan in a single-go without repeated entries into the anterior chamber. Methods: This retrospective non-comparative study was conducted at a referral center and included 12 patients. The one-step approach is described in a step-wise manner. No complications were observed among the patients. Results: One single injection of intracameral melphalan proved to be a successful treatment in nine cases. Two patients required a second injection, which was administered two weeks after the first one following the same technique. Conclusions: This proved to be a reasonable technique for the smooth application of melphalan in the anterior chamber studded with retinoblastoma seeds. Our outcomes revealed that it is an effective, quick, and cost-effective technique. Longer-term data collection is underway, though initial findings are encouraging.en
dc.description.statusPeer reviewed
dc.format.extent4
dc.format.extent1136940
dc.identifier.citationBorroni, D, Bonzano, C, Rachwani-Anil, R, Rocha-de Lossada, C, Martín, F Z, Garcia-Lorente, M, Bonzano, E & Khaqan, H A 2021, 'Less is more : new one-step intracameral chemotherapy technique', Romanian journal of ophthalmology, vol. 65, no. 3, pp. 218-221. https://doi.org/10.22336/rjo.2021.44
dc.identifier.doi10.22336/rjo.2021.44
dc.identifier.issn2457-4325
dc.identifier.otherPubMedCentral: PMC8697783
dc.identifier.otherMendeley: fbb4efa0-1c2c-3f90-877a-a88715701e2b
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/7633
dc.identifier.urlhttps://www.mendeley.com/catalogue/fbb4efa0-1c2c-3f90-877a-a88715701e2b/
dc.identifier.urlhttps://www-webofscience-com.db.rsu.lv/wos/alldb/full-record/MEDLINE:35036640
dc.language.isoeng
dc.relation.ispartofRomanian journal of ophthalmology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAntineoplastic Agents, Alkylating/therapeutic use
dc.subjectHumans
dc.subjectInfant
dc.subjectMelphalan
dc.subjectRetinal Neoplasms
dc.subjectRetinoblastoma
dc.subjectRetrospective Studies
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.titleLess is more : new one-step intracameral chemotherapy techniqueen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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