Please use this identifier to cite or link to this item:
10.1097/APO.0000000000000420
Title: | A New Surgical Technique to Deliver Riboflavin Beneath Corneal Epithelium : The Corneal Cross-Linking Epi-Pocket |
Authors: | Borroni, Davide Bonzano, Chiara Hristova, Rozaliya Sánchez González, José María Pennisi, Flavia Rocha-Bogas, Aurelio Rocha de Lossada, Carlos Department of Doctoral Studies |
Keywords: | corneal epithelium;corneal cross-linking epi-pocket;keratoconus;riboflavin;3.2 Clinical medicine;1.1. Scientific article indexed in Web of Science and/or Scopus database;Ophthalmology |
Issue Date: | 14-Sep-2021 |
Citation: | Borroni , D , Bonzano , C , Hristova , R , Sánchez González , J M , Pennisi , F , Rocha-Bogas , A & Rocha de Lossada , C 2021 , ' A New Surgical Technique to Deliver Riboflavin Beneath Corneal Epithelium : The Corneal Cross-Linking Epi-Pocket ' , Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) , vol. 10 , no. 5 , pp. 495-498 . https://doi.org/10.1097/APO.0000000000000420 |
Abstract: | PURPOSE: To describe a new technique to deliver riboflavin into the corneal stroma during Corneal Cross-Linking (CXL) without the removal of corneal epithelium. METHODS: Keratoconus patients underwent CXL for progressive keratoconus. Riboflavin was delivered by manually creating an epithelial pocket (CXL Epi-Pocket). Verbal rating scale was recorded postoperatively. Best-corrected visual acuity, keratometric indices, corneal thickness and corneal densitometry were recorded at baseline and at 12-month follow-up. RESULTS: Eighteen eyes of 18 patients were included in the study. At a 12-month follow-up, best-corrected visual acuity, K1, K2 and densitometry values were stable. Maximum keratometry (Kmax) reduced from 55.31 ± 6.21 (SD) to 52.34d ± 4.12d (SD) (P value = 0.032). the thinnest point went from 441 ± 21.18 (SD) to 425.4 ± 19.02 (SD) um (P value = 0.041). The verbal rating scale at 1, 2 and 3 days postoperatively were 1.76 ± 0.19 (SD), 1.02 ± 0.51 (SD) and 0.28 ± 0.14 (SD). CONCLUSIONS: CXL Epi-Pocket is able to deliver riboflavin to halt the progression of keratoconus at a 12-month follow-up. |
Description: | Publisher Copyright: Copyright © 2021 Asia-Pacific Academy of Ophthalmology. Published by Wolters Kluwer Health, Inc. on behalf of the Asia-Pacific Academy of Ophthalmology. |
DOI: | 10.1097/APO.0000000000000420 |
ISSN: | 2162-0989 |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
File | Size | Format | |
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A_New_Surgical_Technique_to_Deliver_Riboflavin.pdf | 249.91 kB | Adobe PDF | View/Open |
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