A New Surgical Technique to Deliver Riboflavin Beneath Corneal Epithelium : The Corneal Cross-Linking Epi-Pocket

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dc.contributor.authorBorroni, Davide
dc.contributor.authorBonzano, Chiara
dc.contributor.authorHristova, Rozaliya
dc.contributor.authorSánchez González, José María
dc.contributor.authorPennisi, Flavia
dc.contributor.authorRocha-Bogas, Aurelio
dc.contributor.authorRocha de Lossada, Carlos
dc.contributor.institutionDepartment of Doctoral Studies
dc.date.accessioned2022-02-19T20:40:02Z
dc.date.available2022-02-19T20:40:02Z
dc.date.issued2021-09-14
dc.descriptionPublisher Copyright: Copyright © 2021 Asia-Pacific Academy of Ophthalmology. Published by Wolters Kluwer Health, Inc. on behalf of the Asia-Pacific Academy of Ophthalmology.
dc.description.abstractPURPOSE: To describe a new technique to deliver riboflavin into the corneal stroma during Corneal Cross-Linking (CXL) without the removal of corneal epithelium. METHODS: Keratoconus patients underwent CXL for progressive keratoconus. Riboflavin was delivered by manually creating an epithelial pocket (CXL Epi-Pocket). Verbal rating scale was recorded postoperatively. Best-corrected visual acuity, keratometric indices, corneal thickness and corneal densitometry were recorded at baseline and at 12-month follow-up. RESULTS: Eighteen eyes of 18 patients were included in the study. At a 12-month follow-up, best-corrected visual acuity, K1, K2 and densitometry values were stable. Maximum keratometry (Kmax) reduced from 55.31 ± 6.21 (SD) to 52.34d ± 4.12d (SD) (P value = 0.032). the thinnest point went from 441 ± 21.18 (SD) to 425.4 ± 19.02 (SD) um (P value = 0.041). The verbal rating scale at 1, 2 and 3 days postoperatively were 1.76 ± 0.19 (SD), 1.02 ± 0.51 (SD) and 0.28 ± 0.14 (SD). CONCLUSIONS: CXL Epi-Pocket is able to deliver riboflavin to halt the progression of keratoconus at a 12-month follow-up.en
dc.description.statusPeer reviewed
dc.format.extent4
dc.format.extent255906
dc.identifier.citationBorroni, D, Bonzano, C, Hristova, R, Sánchez González, J M, Pennisi, F, Rocha-Bogas, A & Rocha de Lossada, C 2021, 'A New Surgical Technique to Deliver Riboflavin Beneath Corneal Epithelium : The Corneal Cross-Linking Epi-Pocket', Asia-Pacific journal of ophthalmology (Philadelphia, Pa.), vol. 10, no. 5, pp. 495-498. https://doi.org/10.1097/APO.0000000000000420
dc.identifier.doi10.1097/APO.0000000000000420
dc.identifier.issn2162-0989
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/7614
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85117739820&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofAsia-Pacific journal of ophthalmology (Philadelphia, Pa.)
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectcorneal epithelium
dc.subjectcorneal cross-linking epi-pocket
dc.subjectkeratoconus
dc.subjectriboflavin
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectOphthalmology
dc.titleA New Surgical Technique to Deliver Riboflavin Beneath Corneal Epithelium : The Corneal Cross-Linking Epi-Pocketen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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