Please use this identifier to cite or link to this item:
10.1186/s13053-022-00209-1
| Title: | Pregnancy after breast cancer in BRCA1/2 mutation carriers |
| Authors: | Maksimenko, Jeļena Irmejs, Arvīds Gardovskis, Jānis Department of Surgery RSU Institute of Oncology |
| Keywords: | 3.1 Basic medicine;3.2 Clinical medicine;1.1. Scientific article indexed in Web of Science and/or Scopus database;SDG 3 - Good Health and Well-being |
| Issue Date: | 21-Jan-2022 |
| Citation: | Maksimenko , J , Irmejs , A & Gardovskis , J 2022 , ' Pregnancy after breast cancer in BRCA1/2 mutation carriers ' , Hereditary Cancer in Clinical Practice , vol. 20 , no. 1 , 3 , pp. 3 . https://doi.org/10.1186/s13053-022-00209-1 , https://doi.org/10.1186/s13053-022-00209-1 |
| Abstract: | Background: Often young women affected with BRCA1/2 positive breast cancer have not finished or even not started their childbearing before the onset of the disease. The aim of our mini-review is to summarize state of art knowledge on pregnancy after breast cancer in BRCA1/2 carriers. Methods: A broad review of the literature was conducted using MEDLINE (via PubMed) for relevant articles published. Main body of the abstract: This review summarizes the impact of different cytotoxic agents on a fertility, fertility preservation, maternal and fetal prognosis after pregnancy in breast cancer survivors with BRCA1/2. Conclusion: According to the existing literature evidence pregnancy after therapy for breast cancer in BRCA carriers is safe for the mother and offspring, but patients’ needs, oncofertility counseling and fertility-sparing strategy should be carefully planned before starting the cytotoxic treatment. |
| Description: | Funding Information: This research is supported (not financially) by the European Reference Network on Genetic Tumour Risk Syndromes (ERN GENTURIS)?Project ID No 739547. ERN GENTURIS is partly co-funded by the European Union within the framework of the Third Health Programme ?ERN-2016?Framework Partnership Agreement 2017?2021. Funding Information: This research is supported (not financially) by the European Reference Network on Genetic Tumour Risk Syndromes (ERN GENTURIS)—Project ID No 739547. ERN GENTURIS is partly co-funded by the European Union within the framework of the Third Health Programme “ERN-2016—Framework Partnership Agreement 2017–2021. Publisher Copyright: © 2022, The Author(s). |
| DOI: | 10.1186/s13053-022-00209-1 |
| ISSN: | 1731-2302 |
| Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
| File | Size | Format | |
|---|---|---|---|
| Pregnancy_after_breast_cancer_in.pdf | 592.42 kB | Adobe PDF | View/Open |
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