Please use this identifier to cite or link to this item: 10.1093/nar/gkab1062
Title: HMDB 5.0 : the Human Metabolome Database for 2022
Authors: Wishart, David S
Guo, AnChi
Oler, Eponine
Wang, Fei
Anjum, Afia
Peters, Harrison
Dizon, Raynard
Sayeeda, Zinat
Tian, Siyang
Lee, Brian L
Berjanskii, Mark
Mah, Robert
Yamamoto, Mai
Jovel, Juan
Torres-Calzada, Claudia
Hiebert-Giesbrecht, Mickel
Lui, Vicki W
Varshavi, Dorna
Varshavi, Dorsa
Allen, Dana
Arndt, David
Khetarpal, Nitya
Sivakumaran, Aadhavya
Harford, Karxena
Sanford, Selena
Yee, Kristen
Cao, Xuan
Budinski, Zachary
Liigand, Jaanus
Zhang, Lun
Zheng, Jiamin
Mandal, Rupasri
Karu, Naama
Dambrova, Maija
Schiöth, Helgi B
Greiner, Russell
Gautam, Vasuk
Keywords: 1.4 Chemical sciences;1.6 Biological sciences;3.1 Basic medicine;1.1. Scientific article indexed in Web of Science and/or Scopus database
Issue Date: 7-Jan-2021
Citation: Wishart , D S , Guo , A , Oler , E , Wang , F , Anjum , A , Peters , H , Dizon , R , Sayeeda , Z , Tian , S , Lee , B L , Berjanskii , M , Mah , R , Yamamoto , M , Jovel , J , Torres-Calzada , C , Hiebert-Giesbrecht , M , Lui , V W , Varshavi , D , Varshavi , D , Allen , D , Arndt , D , Khetarpal , N , Sivakumaran , A , Harford , K , Sanford , S , Yee , K , Cao , X , Budinski , Z , Liigand , J , Zhang , L , Zheng , J , Mandal , R , Karu , N , Dambrova , M , Schiöth , H B , Greiner , R & Gautam , V 2021 , ' HMDB 5.0 : the Human Metabolome Database for 2022 ' , Nucleic Acids Research , vol. 50 , no. D1 , pp. D622-D631 . https://doi.org/10.1093/nar/gkab1062
Abstract: The Human Metabolome Database or HMDB (https://hmdb.ca) has been providing comprehensive reference information about human metabolites and their associated biological, physiological and chemical properties since 2007. Over the past 15 years, the HMDB has grown and evolved significantly to meet the needs of the metabolomics community and respond to continuing changes in internet and computing technology. This year's update, HMDB 5.0, brings a number of important improvements and upgrades to the database. These should make the HMDB more useful and more appealing to a larger cross-section of users. In particular, these improvements include: (i) a significant increase in the number of metabolite entries (from 114 100 to 217 920 compounds); (ii) enhancements to the quality and depth of metabolite descriptions; (iii) the addition of new structure, spectral and pathway visualization tools; (iv) the inclusion of many new and much more accurately predicted spectral data sets, including predicted NMR spectra, more accurately predicted MS spectra, predicted retention indices and predicted collision cross section data and (v) enhancements to the HMDB's search functions to facilitate better compound identification. Many other minor improvements and updates to the content, the interface, and general performance of the HMDB website have also been made. Overall, we believe these upgrades and updates should greatly enhance the HMDB's ease of use and its potential applications not only in human metabolomics but also in exposomics, lipidomics, nutritional science, biochemistry and clinical chemistry.
Description: © The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.
DOI: 10.1093/nar/gkab1062
ISSN: 0305-1048
Appears in Collections:Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure

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