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  2. Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure
  3. Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure
Please use this identifier to cite or link to this item: 10.3390/ijms222312891
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dc.contributor.authorBriede, Inese-
dc.contributor.authorBalodis, Dainis-
dc.contributor.authorGardovskis, Janis-
dc.contributor.authorStrumfa, Ilze-
dc.date.accessioned2021-12-22T09:00:01Z-
dc.date.available2021-12-22T09:00:01Z-
dc.date.issued2021-11-29-
dc.identifier.citationBriede , I , Balodis , D , Gardovskis , J & Strumfa , I 2021 , ' Stemness, inflammation and epithelial–mesenchymal transition in colorectal carcinoma : The intricate network ' , International Journal of Molecular Sciences , vol. 22 , no. 23 , 12891 . https://doi.org/10.3390/ijms222312891-
dc.identifier.issn1661-6596-
dc.identifier.otherunpaywall: 10.3390/ijms222312891-
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/7118-
dc.descriptionFunding Information: The APC was covered by Riga Stradins University. Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.-
dc.description.abstractIn global cancer statistics, colorectal carcinoma (CRC) ranks third by incidence and second by mortality, causing 10.0% of new cancer cases and 9.4% of oncological deaths worldwide. Despite the development of screening programs and preventive measures, there are still high numbers of advanced cases. Multiple problems compromise the treatment of metastatic colorectal cancer, one of these being cancer stem cells—a minor fraction of pluripotent, self-renewing malignant cells capable of maintaining steady, low proliferation and exhibiting an intriguing arsenal of treatment resistance mechanisms. Currently, there is an increasing body of evidence for intricate associations between inflammation, epithelial–mesenchymal transition and cancer stem cells. In this review, we focus on inflammation and its role in CRC stemness development through epithelial–mesenchymal transition.en
dc.format.extent15-
dc.format.extent2865343-
dc.language.isoeng-
dc.relation.ispartofInternational Journal of Molecular Sciences-
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.subjectColorectal cancer-
dc.subjectEpithelial–mesenchymal transition-
dc.subjectImmuno-histochemistry-
dc.subjectInflammation-
dc.subjectStem cells-
dc.subject3.2 Clinical medicine-
dc.subject3.1 Basic medicine-
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database-
dc.subjectCatalysis-
dc.subjectMolecular Biology-
dc.subjectSpectroscopy-
dc.subjectComputer Science Applications-
dc.subjectPhysical and Theoretical Chemistry-
dc.subjectOrganic Chemistry-
dc.subjectInorganic Chemistry-
dc.subjectSDG 3 - Good Health and Well-being-
dc.titleStemness, inflammation and epithelial–mesenchymal transition in colorectal carcinoma : The intricate networken
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/systematicreview-
dc.identifier.doi10.3390/ijms222312891-
dc.contributor.institutionDepartment of Pathology-
dc.contributor.institutionDepartment of Surgery-
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85119973457&partnerID=8YFLogxK-
dc.description.statusPeer reviewed-
Appears in Collections:Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure

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