Please use this identifier to cite or link to this item:
10.3390/medicina57101044
Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Kokaine, Linda | - |
dc.contributor.author | Gardovskis, Andris | - |
dc.contributor.author | Gardovskis, Jānis | - |
dc.date.accessioned | 2021-12-04T12:55:01Z | - |
dc.date.available | 2021-12-04T12:55:01Z | - |
dc.date.issued | 2021-09-30 | - |
dc.identifier.citation | Kokaine , L , Gardovskis , A & Gardovskis , J 2021 , ' Evaluation and predictive factors of complete response in rectal cancer after neoadjuvant chemoradiation therapy ' , Medicina (Lithuania) , vol. 57 , no. 10 , 1044 . https://doi.org/10.3390/medicina57101044 | - |
dc.identifier.issn | 1010-660X | - |
dc.identifier.other | unpaywall: 10.3390/medicina57101044 | - |
dc.identifier.uri | https://dspace.rsu.lv/jspui/handle/123456789/6956 | - |
dc.description | Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. | - |
dc.description.abstract | The response to neoadjuvant chemoradiation therapy is an important prognostic factor for locally advanced rectal cancer. Although the majority of the patients after neoadjuvant therapy are referred to following surgery, the clinical data show that complete clinical or pathological response is found in a significant proportion of the patients. Diagnostic accuracy of confirming the complete response has a crucial role in further management of a rectal cancer patient. As the rate of clinical complete response, unfortunately, is not always consistent with pathological complete response, accurate diagnostic parameters and predictive markers of tumor response may help to guide more personalized treatment strategies and identify potential candidates for nonoperative management more safely. The management of complete response demands interdisciplinary collaboration includ-ing oncologists, radiotherapists, radiologists, pathologists, endoscopists and surgeons, because the absence of a multidisciplinary approach may compromise the oncological outcome. Prediction and improvement of rectal cancer response to neoadjuvant therapy is still an active and challenging field of further research. This literature review is summarizing the main, currently known clinical informa-tion about the complete response that could be useful in case if encountering such condition in rectal cancer patients after neoadjuvant chemoradiation therapy, using as a source PubMed publications from 2010–2021 matching the search terms “rectal cancer”, “neoadjuvant therapy” and “response”. | en |
dc.format.extent | 29 | - |
dc.format.extent | 474283 | - |
dc.language.iso | eng | - |
dc.relation.ispartof | Medicina (Lithuania) | - |
dc.rights | info:eu-repo/semantics/openAccess | - |
dc.subject | Locally advanced rectal cancer | - |
dc.subject | Neoadjuvant therapy | - |
dc.subject | Predictive factors of complete response | - |
dc.subject | Tumor response | - |
dc.subject | 3.2 Clinical medicine | - |
dc.subject | 1.1. Scientific article indexed in Web of Science and/or Scopus database | - |
dc.subject | General Medicine | - |
dc.subject | SDG 3 - Good Health and Well-being | - |
dc.title | Evaluation and predictive factors of complete response in rectal cancer after neoadjuvant chemoradiation therapy | en |
dc.type | /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/systematicreview | - |
dc.identifier.doi | 10.3390/medicina57101044 | - |
dc.contributor.institution | Department of Surgery | - |
dc.identifier.url | http://www.scopus.com/inward/record.url?scp=85116543141&partnerID=8YFLogxK | - |
dc.description.status | Peer reviewed | - |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
File | Size | Format | |
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Evaluation_and_Predictive_Factors_of_Complete_Response.pdf | 463.17 kB | Adobe PDF | View/Open |
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