Please use this identifier to cite or link to this item:
10.2478/prolas-2021-0055
Title: | Renal Survival and Validation of Novel International Immunoglobulin A Nephropathy Prediction Tool in Latvian Population: Preliminary Data |
Authors: | Saulīte, Anna Jana Popova, Anna Erts, Renārs Rācenis, Kārlis Kučāne, Linda Pētersons, Aivars Laurinavičius, Arvydas Čerņevskis, Harijs Kuzema, Viktorija Faculty of Medicine |
Keywords: | end-stage kidney disease;immunoglobulin A nephropathy;kidney survival risk factors;novel IgAN prediction tool;3.2 Clinical medicine;1.1. Scientific article indexed in Web of Science and/or Scopus database |
Issue Date: | Oct-2021 |
Citation: | Saulīte , A J , Popova , A , Erts , R , Rācenis , K , Kučāne , L , Pētersons , A , Laurinavičius , A , Čerņevskis , H & Kuzema , V 2021 , ' Renal Survival and Validation of Novel International Immunoglobulin A Nephropathy Prediction Tool in Latvian Population: Preliminary Data ' , Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences. , vol. 75 , no. 5 , pp. 379-386 . https://doi.org/10.2478/prolas-2021-0055 |
Abstract: | The aim of the study was to determine kidney survival and validate the novel international immunoglobulin A nephropathy (IgAN) prediction tool (PT) in the Latvian population. Adults with morphologically confirmed IgAN were included. Kidney survival was analysed with the Kaplan–Meier method. PT-assigned risk was compared with calculated risk by the Cox regression model. The Kaplan–Meier analysis included 95 patients. The five-year kidney survival Q3 was 24 months. Women had longer median kidney-survival time (> 60 months) than men (58 months). Median kidney survival in participants with MEST T0 was longer than 60 months; T1 and T2 were 40 and 18 months, respectively. Median kidney survival in participants with diastolic blood pressure (DBP) < 99 mmHg was longer than 60 months, whereas in patients with DBP 100–109 and 110 mmHg, it was 40 and 24 months, respectively. Cox regression analysis included 68 patients. A moderate degree of correlation was found between predicted and observed five-year risk (p = 0.001). Gender, tubular atrophy/interstitial fibrosis, DBP are significant factors affecting kidney survival. Since there was statistically significant correlation and reliability between PT and follow-up analysis data, we conclude that PT could be applied for use in the Latvian population |
Description: | Affiliations in Web of Science publication are different from those provided in Scopus database and the original journal publication. Here are given the affiliations from Scopus/original publication in "Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences". |
DOI: | 10.2478/prolas-2021-0055 |
ISSN: | 2255-890X |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
File | Size | Format | |
---|---|---|---|
prolas-2021-0055.pdf | 1.63 MB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.