Please use this identifier to cite or link to this item:
10.3390/biom11081189
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DC Field | Value | Language |
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dc.contributor.author | Gravelsina, Sabine | - |
dc.contributor.author | Nora‐krukle, Zaiga | - |
dc.contributor.author | Vilmane, Anda | - |
dc.contributor.author | Svirskis, Simons | - |
dc.contributor.author | Vecvagare, Katrine | - |
dc.contributor.author | Krūmiņa, Angelika | - |
dc.contributor.author | Murovska, Modra | - |
dc.date.accessioned | 2021-09-15T13:50:01Z | - |
dc.date.available | 2021-09-15T13:50:01Z | - |
dc.date.issued | 2021-08-11 | - |
dc.identifier.citation | Gravelsina , S , Nora‐krukle , Z , Vilmane , A , Svirskis , S , Vecvagare , K , Krūmiņa , A & Murovska , M 2021 , ' Potential of activin b as a clinical biomarker in myalgic encephalomyelitis/chronic fatigue syndrome (Me/cfs) ' , Biomolecules , vol. 11 , no. 8 , 1189 . https://doi.org/10.3390/biom11081189 | - |
dc.identifier.issn | 2218-273X | - |
dc.identifier.other | unpaywall: 10.3390/biom11081189 | - |
dc.identifier.uri | https://dspace.rsu.lv/jspui/handle/123456789/6355 | - |
dc.description | Funding Information: This research was funded by the Latvian Science Council?s Fundamental and Applied Research project, grant number LZP?2019/1?0380. Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. | - |
dc.description.abstract | Reliable serum biomarkers are of immense need for diagnostic purposes of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)—a disabling and complex disease for which diagnosis is mainly based on clinical symptoms. The aim of this study was to evaluate a possible diagnostic potential of activin B by directly comparing 134 cases of ME/CFS with 54 healthy controls. Analyses of human activin B level in plasma samples were performed using a validated human activin B ELISA assay. The results of the study show that activin B levels did not differ statistically significantly between ME/CFS patients and healthy controls (p = 0.6511). No gender or age‐related differences in activin B levels were observed in the ME/CFS group and healthy controls. The level of activin B tended to decrease with increasing visual analogue scale score (r = −0.2004; p = 0.5085) nevertheless the results obtained so far does not support the clinical utility of activin B as a bi-omarker for ME/CFS. | en |
dc.format.extent | 9 | - |
dc.format.extent | 1374451 | - |
dc.language.iso | eng | - |
dc.relation.ispartof | Biomolecules | - |
dc.rights | info:eu-repo/semantics/openAccess | - |
dc.subject | Human activin B | - |
dc.subject | ME/CFS | - |
dc.subject | Visual analogue scale | - |
dc.subject | 3.1 Basic medicine | - |
dc.subject | 1.1. Scientific article indexed in Web of Science and/or Scopus database | - |
dc.subject | Biochemistry | - |
dc.subject | Molecular Biology | - |
dc.subject | SDG 3 - Good Health and Well-being | - |
dc.title | Potential of activin b as a clinical biomarker in myalgic encephalomyelitis/chronic fatigue syndrome (Me/cfs) | en |
dc.type | /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article | - |
dc.identifier.doi | 10.3390/biom11081189 | - |
dc.contributor.institution | Institute of Microbiology and Virology | - |
dc.contributor.institution | Department of Infectology | - |
dc.identifier.url | http://www.scopus.com/inward/record.url?scp=85112184644&partnerID=8YFLogxK | - |
dc.description.status | Peer reviewed | - |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
File | Size | Format | |
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Potential_of_Activin_B_as_a_Clinical_Biomarker.pdf | 1.34 MB | Adobe PDF | View/Open |
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