Please use this identifier to cite or link to this item:
10.12697/poa.2020.29.2.02
| Title: | Factors affecting facial development and formation of cleft lip and palate : a literature review |
| Authors: | Vaivads, Mārtiņš Balode, Evija Pilmane, Māra Department of Morphology |
| Keywords: | cleft lip;cleft palate;genes;growth factors;3.1 Basic medicine;1.1. Scientific article indexed in Web of Science and/or Scopus database |
| Issue Date: | 2020 |
| Citation: | Vaivads , M , Balode , E & Pilmane , M 2020 , ' Factors affecting facial development and formation of cleft lip and palate : a literature review ' , Papers on Anthropology , vol. 29 , no. 2 , pp. 22-35 . https://doi.org/10.12697/poa.2020.29.2.02 |
| Abstract: | The craniofacial region forms in a complicated developmental process regu-lated by multiple genes and growth factors. Disruption and dysregulation during facial development can lead to multiple congenital facial anomalies including cleft lip and palate. This literature review collects and analyses the existing information about the interaction of multiple growth factors and genes within the developing facial region and their association with facial pathology. The factors analysed in this review are DLX4, FOXE1, HOXB3, MSX2, PAX7, PAX9, RYK, SHH, SOX3, WNT3A, WNT9B and BARX1. |
| DOI: | 10.12697/poa.2020.29.2.02 |
| ISSN: | 1736-7646 |
| Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
| File | Size | Format | |
|---|---|---|---|
| Factors_affecting_facial_development.pdf | 150.74 kB | Adobe PDF | View/Open |
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