Please use this identifier to cite or link to this item:
10.18502/ijrm.v19i6.9372
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DC Field | Value | Language |
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dc.contributor.author | Kreicberga, Ilze | - |
dc.contributor.author | Junga, Anna | - |
dc.contributor.author | Pilmane, Māra | - |
dc.date.accessioned | 2021-08-02T07:30:01Z | - |
dc.date.available | 2021-08-02T07:30:01Z | - |
dc.date.issued | 2021-06 | - |
dc.identifier.citation | Kreicberga , I , Junga , A & Pilmane , M 2021 , ' Assessment of apoptosis and appearance of hepatocyte growth factor in placenta at different gestational ages : A cross-sectional study ' , International Journal of Reproductive BioMedicine , vol. 19 , no. 6 , pp. 505-514 . https://doi.org/10.18502/ijrm.v19i6.9372 | - |
dc.identifier.issn | 2476-4108 | - |
dc.identifier.uri | https://dspace.rsu.lv/jspui/handle/123456789/5910 | - |
dc.description | Funding Information: The authors acknowledge the kind support of Riga Stradins University, Riga, Latvia in facilitating the study. Publisher Copyright: © 2021, Research and Clinical Center for Infertitlity. All rights reserved. | - |
dc.description.abstract | Background: Fetal growth is determined by the interaction between mother and fetus using the placental interface throughout the pregnancy. Objective: To research apoptosis and appearance of hepatocyte growth factor (HGF) in placentas of different gestational ages and to describe the anthropometrical and clinical indices of mothers and newborns. Materials and Methods: The study material was obtained from 53 human immunodeficiency virus negative pregnant women of legal age without systemic diseases. The staining of placental apoptotic cells was processed by a standard in situ cell death detection kit. The detection of HGF was provided by the ImmunoCruz goat ABC Staining System protocol sc-2023. Relative distribution of positive structures was evaluated using the semiquantitative counting method. Results: The mean rank value of the amount of HGF-containing cells (cytotrophoblasts, syncytiotrophoblasts, extravillous trophoblasts, Höfbauer cells, and cells of extraembryonic mesoderm) was 1.61 ± 0.94. Apoptotic cells (cytotrophoblasts, syncytiotrophoblasts, extravillous trophoblasts, and cells of extraembryonic mesoderm) were found in all placental samples of various gestational ages (term 13.00 ± 13.05 and preterm 27.00 ± 18.25); in general, their amount decreased with advancing gestational age of the placenta (p < 0.01). Conclusion: Weight of a placenta directly depends on the gestational age and correlates with the main fetal anthropometrical parameters (weight, length, and head and chest circumferences). The decrease in HGF-containing and apoptotic cells with advancing gestation depends on the adaptation potential of the placenta, proving the other ways of cellular disposition. | en |
dc.format.extent | 10 | - |
dc.format.extent | 715600 | - |
dc.language.iso | eng | - |
dc.relation.ispartof | International Journal of Reproductive BioMedicine | - |
dc.rights | info:eu-repo/semantics/openAccess | - |
dc.subject | Pregnancy | - |
dc.subject | Placenta | - |
dc.subject | Gestational age | - |
dc.subject | Apoptosis | - |
dc.subject | Immunohistochemistry | - |
dc.subject | 3.1 Basic medicine | - |
dc.subject | 1.1. Scientific article indexed in Web of Science and/or Scopus database | - |
dc.subject | Embryology | - |
dc.subject | SDG 3 - Good Health and Well-being | - |
dc.title | Assessment of apoptosis and appearance of hepatocyte growth factor in placenta at different gestational ages : A cross-sectional study | en |
dc.type | /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article | - |
dc.identifier.doi | 10.18502/ijrm.v19i6.9372 | - |
dc.contributor.institution | Institute of Anatomy and Anthropology | - |
dc.identifier.url | http://www.scopus.com/inward/record.url?scp=85111578507&partnerID=8YFLogxK | - |
dc.identifier.url | http://journals.ssu.ac.ir/ijrmnew/article-1-1797-en.html | - |
dc.description.status | Peer reviewed | - |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
File | Size | Format | |
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Assessment_of_apoptosis_and_appearance.pdf | 698.83 kB | Adobe PDF | View/Open |
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