Please use this identifier to cite or link to this item:
10.1177/0009922810394838
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DC Field | Value | Language |
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dc.contributor.author | Rimoin, Anne W. | - |
dc.contributor.author | Hoff, Nicole A. | - |
dc.contributor.author | Fischer Walker, Christa L. | - |
dc.contributor.author | Hamza, Hala S. | - |
dc.contributor.author | Vince, Adriana | - |
dc.contributor.author | Rahman, Naglaa Abdel | - |
dc.contributor.author | Andrasevic, Sasa | - |
dc.contributor.author | Emam, Soha | - |
dc.contributor.author | Vukelic, Dubravka | - |
dc.contributor.author | Elminawi, Nevine | - |
dc.contributor.author | Ghafar, Hadeer Abdel | - |
dc.contributor.author | Da Cunha, Antonia L.A. | - |
dc.contributor.author | Qazi, Shamim | - |
dc.contributor.author | Gardovska, Dace | - |
dc.contributor.author | Steinhoff, Mark C. | - |
dc.date.accessioned | 2021-07-15T07:55:01Z | - |
dc.date.available | 2021-07-15T07:55:01Z | - |
dc.date.issued | 2011-06 | - |
dc.identifier.citation | Rimoin , A W , Hoff , N A , Fischer Walker , C L , Hamza , H S , Vince , A , Rahman , N A , Andrasevic , S , Emam , S , Vukelic , D , Elminawi , N , Ghafar , H A , Da Cunha , A L A , Qazi , S , Gardovska , D & Steinhoff , M C 2011 , ' Treatment of streptococcal pharyngitis with once-daily amoxicillin versus intramuscular benzathine penicillin g in low-resource settings : A randomized controlled trial ' , Clinical Pediatrics , vol. 50 , no. 6 , pp. 535-542 . https://doi.org/10.1177/0009922810394838 | - |
dc.identifier.issn | 0009-9228 | - |
dc.identifier.uri | https://dspace.rsu.lv/jspui/handle/123456789/5883 | - |
dc.description.abstract | Background: Primary prevention of acute rheumatic fever is achieved by proper antibiotic treatment of group A β -hemolytic streptococcal (GAS) pharyngitis. Methods: To assess noninferiority of oral amoxicillin to intramuscular benzathine penicillin G (IM BPG). Children (2 to 12 years) meeting enrollment criteria were randomized 1:1 to receive antibiotic treatment in 2 urban outpatient clinics in Egypt and Croatia. Results: A total of 558 children (Croatia = 166, Egypt = 392) were randomized, with 368 evaluable in an intention-to-treat (ITT) analysis, and 272 evaluable in the per protocol (PP) analysis. In Croatia, ITT and PP treatment success rates were comparable for IM BPG and amoxicillin (2.5% difference vs 1.1% difference, respectively). In Egypt, amoxicillin was not comparable with IM BPG in ITT analysis (15.1% difference), but was comparable in PP analysis (-9.3% difference). Conclusion: If compliance is a major issue, a single dose of IM BPG may be preferable for treatment of GAS pharyngitis. | en |
dc.format.extent | 8 | - |
dc.format.extent | 190844 | - |
dc.language.iso | eng | - |
dc.relation.ispartof | Clinical Pediatrics | - |
dc.rights | info:eu-repo/semantics/openAccess | - |
dc.subject | amoxicillin | - |
dc.subject | intramuscular benzathine penicillin G | - |
dc.subject | randomized clinical trial | - |
dc.subject | streptococcal pharyngitis | - |
dc.subject | 3.2 Clinical medicine | - |
dc.subject | 1.1. Scientific article indexed in Web of Science and/or Scopus database | - |
dc.subject | Pediatrics, Perinatology, and Child Health | - |
dc.title | Treatment of streptococcal pharyngitis with once-daily amoxicillin versus intramuscular benzathine penicillin g in low-resource settings : A randomized controlled trial | en |
dc.type | /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article | - |
dc.identifier.doi | 10.1177/0009922810394838 | - |
dc.contributor.institution | Rīga Stradiņš University | - |
dc.identifier.url | http://www.scopus.com/inward/record.url?scp=79956100472&partnerID=8YFLogxK | - |
dc.description.status | Peer reviewed | - |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
File | Size | Format | |
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Treatment_of_streptococcal_pharyngitis_with_once_daily_amoxicillin.pdf | 186.37 kB | Adobe PDF | View/Open |
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