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  2. Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure
  3. Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure
Please use this identifier to cite or link to this item: 10.2478/v10046-009-0029-2
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dc.contributor.authorPjanova, Dace-
dc.contributor.authorAzarjana, Kristīne-
dc.contributor.authorČema, Ingrida-
dc.contributor.authorHeisele, Olita-
dc.date.accessioned2021-06-15T11:30:01Z-
dc.date.available2021-06-15T11:30:01Z-
dc.date.issued2009-
dc.identifier.citationPjanova , D , Azarjana , K , Čema , I & Heisele , O 2009 , ' Genetic alteration in melanoma development ' , Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences , vol. 63 , no. 3 , pp. 73-80 . https://doi.org/10.2478/v10046-009-0029-2-
dc.identifier.issn1407-009X-
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/5039-
dc.descriptionFunding Information: We acknowledge a grant from the European Social Fund (ESF) programme No. ESS2004/3.-
dc.description.abstractThe transition from a normal to a neoplastic cell is a complex process and involves many sequential genetic events. Over the last several years, substantial progress has been made in the understanding of molecular biology of melanoma including its development, progression, and resistance to therapy. An important step in cancer development appears to be senescence - a crucial barrier that prevents the proliferation of cells that are at different stages of malignancy. This review is mainly focused on patterns of molecular changes in the different steps of neoplastic transformation in melanoma and provides an up-to-date view on our understanding of the molecular genetics of melanoma development as well as therapeutic approaches based on this knowledge.en
dc.format.extent8-
dc.format.extent191448-
dc.language.isoeng-
dc.relation.ispartofProceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences-
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.subjectCancer-
dc.subjectGenes-
dc.subjectGenetics-
dc.subjectMelanoma-
dc.subjectMutations-
dc.subject3.2 Clinical medicine-
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database-
dc.subjectGeneral-
dc.subjectSDG 3 - Good Health and Well-being-
dc.titleGenetic alteration in melanoma developmenten
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/systematicreview-
dc.identifier.doi10.2478/v10046-009-0029-2-
dc.contributor.institutionRīga Stradiņš University-
dc.contributor.institutionDepartment of Oral Medicine-
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=72849109854&partnerID=8YFLogxK-
dc.description.statusPeer reviewed-
Appears in Collections:Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure

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