Please use this identifier to cite or link to this item:
10.1016/j.medici.2015.01.004
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kakurina, Natalja | - |
dc.contributor.author | Kadisa, Anda | - |
dc.contributor.author | Lejnieks, Aivars | - |
dc.contributor.author | Mikazane, Helena | - |
dc.contributor.author | Kozireva, Svetlana | - |
dc.contributor.author | Murovska, Modra | - |
dc.date.accessioned | 2021-05-28T11:15:01Z | - |
dc.date.available | 2021-05-28T11:15:01Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | Kakurina , N , Kadisa , A , Lejnieks , A , Mikazane , H , Kozireva , S & Murovska , M 2015 , ' Use of exploratory factor analysis to ascertain the correlation between the activities of rheumatoid arthritis and infection by human parvovirus B19 ' , Medicina (Lithuania) , vol. 51 , no. 1 , pp. 18-24 . https://doi.org/10.1016/j.medici.2015.01.004 | - |
dc.identifier.issn | 1010-660X | - |
dc.identifier.uri | https://dspace.rsu.lv/jspui/handle/123456789/4563 | - |
dc.description | Funding Information: This study was supported in part by the grant 09.1112 of the Latvian Council of Sciences and National Program in Biomedicine (2009–2013). Publisher Copyright: © 2015 Lithuanian University of Health Sciences. Copyright: Copyright 2016 Elsevier B.V., All rights reserved. | - |
dc.description.abstract | Background and objective: We evaluated a possible correlation between the clinical activities of rheumatoid arthritis (RA) and human parvovirus B19 (B19) infection using exploratory factor analysis (EFA). Materials and methods: RA patients were organized into two groups: 100 patients in the main group and 97 in the RA(DAS28) group. Four subgroups were defined from the main group according to the presence or absence of certain infection-specific markers: group I comprised 43 patients who had IgG antibodies against B19; group II, 25 patients with active B19 infection (B19-specific IgM antibodies and/or plasma viremia); group III, 19 patients with latent/persistent B19 infection (virus-specific sequences in peripheral blood leukocytes' DNA with or without B19-specific IgG antibodies), and group IV, 13 patients without infection markers. The RA(DAS28) group was divided into four subgroups similarly to the main group: group I, 35; group II, 31; group III, 19; and group IV, 12 patients. Disease-specific clinical values in both groups were analyzed employing EFA, and the RA(DAS28) group was additionally assessed using Disease Activity Score (DAS)28. Results: RA activity was higher in patients who had markers of B19 infection. The highest activity of RA in both study groups was in patients with latent/persistent infection. In the RA(DAS28) group, according to DAS28, the highest activity of RA was in patients with active B19 infection. Conclusions: Using EFA and DAS28, a correlation between the clinical activity of RA and B19 infection was confirmed. These data suggest that EFA is applicable for medico-biological studies. | en |
dc.format.extent | 7 | - |
dc.format.extent | 1026086 | - |
dc.language.iso | eng | - |
dc.relation.ispartof | Medicina (Lithuania) | - |
dc.rights | info:eu-repo/semantics/openAccess | - |
dc.subject | Exploratory factor analysis | - |
dc.subject | Human parvovirus B19 | - |
dc.subject | Rheumatoid arthritis | - |
dc.subject | 3.2 Clinical medicine | - |
dc.subject | 1.6 Biological sciences | - |
dc.subject | 3.1 Basic medicine | - |
dc.subject | 1.1. Scientific article indexed in Web of Science and/or Scopus database | - |
dc.subject | General Medicine | - |
dc.subject | SDG 3 - Good Health and Well-being | - |
dc.title | Use of exploratory factor analysis to ascertain the correlation between the activities of rheumatoid arthritis and infection by human parvovirus B19 | en |
dc.type | /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article | - |
dc.identifier.doi | 10.1016/j.medici.2015.01.004 | - |
dc.contributor.institution | Department of Internal Diseases | - |
dc.contributor.institution | Institute of Microbiology and Virology | - |
dc.identifier.url | http://www.scopus.com/inward/record.url?scp=84951977658&partnerID=8YFLogxK | - |
dc.description.status | Peer reviewed | - |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
File | Size | Format | |
---|---|---|---|
Use_of_exploratory_factor_analysis.pdf | 1 MB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.