Please use this identifier to cite or link to this item:
10.12659/AJCR.909778
Title: | Chronic Thromboembolic Pulmonary Hypertension and Antiphospholipid Syndrome with Immune Thrombocytopenia : A Case Report |
Authors: | Skride, Andris Sablinskis, Matiss Sablinskis, Kristaps Lejniece, Sandra Lejnieks, Aivars Klepetko, Walter Lang, Irene M. Rīga Stradiņš University |
Keywords: | Antiphospholipid Syndrome;Hypotension;pulmonary;purpura;Thrombocytopenic;Idiopathic;3.2 Clinical medicine;1.1. Scientific article indexed in Web of Science and/or Scopus database;General Medicine |
Issue Date: | 19-Oct-2018 |
Citation: | Skride , A , Sablinskis , M , Sablinskis , K , Lejniece , S , Lejnieks , A , Klepetko , W & Lang , I M 2018 , ' Chronic Thromboembolic Pulmonary Hypertension and Antiphospholipid Syndrome with Immune Thrombocytopenia : A Case Report ' , The American journal of case reports , vol. 19 , pp. 1245-1248 . https://doi.org/10.12659/AJCR.909778 |
Abstract: | BACKGROUND Antiphospholipid syndrome is an autoimmune disorder characterized by a hypercoagulable state associated with circulating antiphospholipid antibodies. The presence of antiphospholipid antibodies can result in a variety of clinical symptoms, such as thrombocytopenia, stillbirth, endocardial pathologies, and recurrent pulmonary embolism. CASE REPORT We present the case of a 23-year-old man with antiphospholipid syndrome and chronic thromboembolic pulmonary hypertension who developed severe thrombocytopenia. The patient died from right heart failure before the thrombocytopenia could be managed, preventing performance of a pulmonary endarterectomy procedure. CONCLUSIONS Managing platelet counts in patients with antiphospholipid syndrome prior to major surgery is very problematic, and requires similar treatment strategy as in patients with immune thrombocytic thrombocytopenia. Platelet transfusions may further decrease platelet count, as it can trigger formation of new antibodies. |
DOI: | 10.12659/AJCR.909778 |
ISSN: | 1941-5923 |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
File | Size | Format | |
---|---|---|---|
Chronic_Thromboembolic_Pulmonary.pdf | 79.62 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.