Please use this identifier to cite or link to this item:
10.3390/microorganisms12020362
Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Sokolovska, Liba | - |
dc.contributor.author | Cistjakovs, Maksims | - |
dc.contributor.author | Matroze, Asnate | - |
dc.contributor.author | Murovska, Modra | - |
dc.contributor.author | Sultanova, Alina | - |
dc.date.accessioned | 2024-03-22T08:55:01Z | - |
dc.date.available | 2024-03-22T08:55:01Z | - |
dc.date.issued | 2024-02-09 | - |
dc.identifier.citation | Sokolovska , L , Cistjakovs , M , Matroze , A , Murovska , M & Sultanova , A 2024 , ' From Viral Infection to Autoimmune Reaction : Exploring the Link between Human Herpesvirus 6 and Autoimmune Diseases ' , Microorganisms , vol. 12 , no. 2 , 362 , pp. 1-18 . https://doi.org/10.3390/microorganisms12020362 , https://doi.org/10.3390/microorganisms12020362 | - |
dc.identifier.issn | 2076-2607 | - |
dc.identifier.other | PubMedCentral: PMC10892088 | - |
dc.identifier.other | unpaywall: 10.3390/microorganisms12020362 | - |
dc.identifier.other | Mendeley: 8abe9c97-fcde-3d1f-b39f-d02cb1d156a6 | - |
dc.identifier.uri | https://dspace.rsu.lv/jspui/handle/123456789/15394 | - |
dc.description | Publisher Copyright: © 2024 by the authors. | - |
dc.description.abstract | The complexity of autoimmunity initiation has been the subject of many studies. Both genetic and environmental factors are essential in autoimmunity development. Among others, environmental factors include infectious agents. HHV-6 is a ubiquitous human pathogen with a high global prevalence. It has several properties suggestive of its contribution to autoimmunity development. HHV-6 has a broad cell tropism, the ability to establish latency with subsequent reactivation and persistence, and a range of immunomodulation capabilities. Studies have implicated HHV-6 in a plethora of autoimmune diseases-endocrine, neurological, connective tissue, and others-with some studies even proposing possible autoimmunity induction mechanisms. HHV-6 can be frequently found in autoimmunity-affected tissues and lesions; it has been found to infect autoimmune-pathology-relevant cells and influence immune responses and signaling. This review highlights some of the most well-known autoimmune conditions to which HHV-6 has been linked, like multiple sclerosis and autoimmune thyroiditis, and summarizes the data on HHV-6 involvement in autoimmunity development. | en |
dc.format.extent | 18 | - |
dc.format.extent | 1294143 | - |
dc.language.iso | eng | - |
dc.relation.ispartof | Microorganisms | - |
dc.rights | info:eu-repo/semantics/openAccess | - |
dc.subject | HHV-6 | - |
dc.subject | human herpesvirus 6 | - |
dc.subject | autoimmunity | - |
dc.subject | autoimmune disease | - |
dc.subject | multiple sclerosis | - |
dc.subject | systemic sclerosis | - |
dc.subject | inflammatory bowel disease | - |
dc.subject | autoimmune thyroiditis | - |
dc.subject | chronic fatigue syndrome | - |
dc.subject | 3.3 Health sciences | - |
dc.subject | 3.1 Basic medicine | - |
dc.subject | 1.1. Scientific article indexed in Web of Science and/or Scopus database | - |
dc.subject | SDG 3 - Good Health and Well-being | - |
dc.title | From Viral Infection to Autoimmune Reaction : Exploring the Link between Human Herpesvirus 6 and Autoimmune Diseases | en |
dc.type | /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/systematicreview | - |
dc.identifier.doi | 10.3390/microorganisms12020362 | - |
dc.contributor.institution | Institute of Microbiology and Virology | - |
dc.identifier.url | http://www.scopus.com/inward/record.url?scp=85187261458&partnerID=8YFLogxK | - |
dc.description.status | Peer reviewed | - |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
File | Size | Format | |
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From_Viral_Infection_to_Autoimmune_Reaction.pdf | 1.26 MB | Adobe PDF | View/Open |
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