Please use this identifier to cite or link to this item:
10.3390/medicina59112017
Title: | Age-Based Comparative Analysis of Colorectal Cancer Colonoscopy Screening Findings |
Authors: | Vilkoite, Ilona Tolmanis, Ivars Abu Meri, Hosams Polaka, Inese Mezmale, Linda Lejnieks, Aivars Department of Doctoral Studies Department of Internal Diseases |
Keywords: | Humans;Middle Aged;Colonic Polyps/diagnostic imaging;Early Detection of Cancer;Colonoscopy;Colorectal Neoplasms/diagnosis;Adenoma/diagnostic imaging;3.2 Clinical medicine;1.1. Scientific article indexed in Web of Science and/or Scopus database;SDG 3 - Good Health and Well-being |
Issue Date: | 16-Nov-2023 |
Citation: | Vilkoite , I , Tolmanis , I , Abu Meri , H , Polaka , I , Mezmale , L & Lejnieks , A 2023 , ' Age-Based Comparative Analysis of Colorectal Cancer Colonoscopy Screening Findings ' , Medicina (Kaunas, Lithuania) , vol. 59 , no. 11 , 2017 . https://doi.org/10.3390/medicina59112017 |
Abstract: | Background and Objectives: Colorectal cancer (CRC) incidence is rapidly emerging among individuals <50 years, termed as early-onset colorectal cancer (EOCRC). This study aimed to probe variations in tumorigenic pathology and relevant manifestations (polyp and adenoma incidence) between suspected cases of EOCRC and late-onset CRC (LOCRC; ≥50 years of age). Materials and Methods: Between September 2022 and February 2023, colonoscopy-based screening data from 1653 patients were included in this study. All eligible participants were divided into two groups, depending upon patient age, where Group 1 consisted of 1021 patients aged <50 years while Group 2 consisted of 632 patients aged ≥ 50 years. Polyp samples were collected when identified peri-procedurally and characterized according to World Health Organization criteria. Results: Polyp detection rate was 42% for the <50-year age group, while this was 76% for the ≥50-year age group. Additionally, the <50-year age group predominated in hyperplastic polyp manifestation, particularly within the rectum and sigmoid colon. In addition, the ≥50-year age group had increased prevalence of serrated polyps and differing adenoma manifestations. Conclusions: This investigation served to highlight the importance of age stratification for CRC colonoscopy-based screening effectiveness, with particular reference to evaluations that are based on polyp localization within differing colon regions. |
Description: | Publisher Copyright: © 2023 by the authors. |
DOI: | 10.3390/medicina59112017 |
ISSN: | 1010-660X |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
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