Please use this identifier to cite or link to this item:
10.3390/medicina59061082
Title: | Functional Disability and Brain MRI Volumetry Results among Multiple Sclerosis Patients during 5-Year Follow-Up |
Authors: | Strautmane, Sintija Balodis, Arturs Teivāne, Agnete Grabovska, Dagnija Naudiņš, Edgars Urbanovics, Daniels Fišermans, Edgars Mednieks, Jānis Flintere-Flinta, Alīna Priede, Zanda Millers, Andrejs Zolovs, Maksims Department of Radiology Department of Neurology and Neurosurgery Statistics Unit |
Keywords: | multiple sclerosis;brain atrophy;MRI;EDSS;disability;3.2 Clinical medicine;1.1. Scientific article indexed in Web of Science and/or Scopus database |
Issue Date: | 4-Jun-2023 |
Citation: | Strautmane , S , Balodis , A , Teivāne , A , Grabovska , D , Naudiņš , E , Urbanovics , D , Fišermans , E , Mednieks , J , Flintere-Flinta , A , Priede , Z , Millers , A & Zolovs , M 2023 , ' Functional Disability and Brain MRI Volumetry Results among Multiple Sclerosis Patients during 5-Year Follow-Up ' , Medicina , vol. 59 , no. 6 , 1082 . https://doi.org/10.3390/medicina59061082 |
Abstract: | Background and Objectives: We aimed to determine the link between brain volumetry results and functional disability calculated using the Expanded Disability Status Scale (EDSS) among multiple sclerosis (MS) patients in relation to the provided treatment (disease-modifying therapies (DMTs)) during a 5-year follow-up period. Materials and Methods: A retrospective cohort study was performed enrolling 66 consecutive patients with a confirmed diagnosis of MS, predominantly females (62% (n = 41)). Relapsing–remitting (RR) MS was noted in 92% (n = 61) of patients, with the rest being patients with secondary progressive (SP) MS. The mean age was 43.3 years (SD 8.3 years). |
Description: | Funding Information: This research was funded by the Pauls Stradins Clinical University Hospital Scientific Institute Research Grant. Publisher Copyright: © 2023 by the authors. |
DOI: | 10.3390/medicina59061082 |
ISSN: | 0025-7680 |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
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Functional_Disability_and_Brain_MRI_Volumetry.pdf | 1.55 MB | Adobe PDF | View/Open |
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