Please use this identifier to cite or link to this item:
10.1155/2022/1315299
Title: | Corneal Endothelial Cell Loss in Glaucoma and Glaucoma Surgery and the Utility of Management with Descemet Membrane Endothelial Keratoplasty (DMEK) |
Authors: | Vallabh, Neeru A. Kennedy, Stephnie Vinciguerra, Riccardo McLean, Keri Levis, Hannah Borroni, Davide Romano, Vito Willoughby, Colin E. Department of Doctoral Studies |
Keywords: | 3.2 Clinical medicine;1.1. Scientific article indexed in Web of Science and/or Scopus database;Ophthalmology |
Issue Date: | 2022 |
Citation: | Vallabh , N A , Kennedy , S , Vinciguerra , R , McLean , K , Levis , H , Borroni , D , Romano , V & Willoughby , C E 2022 , ' Corneal Endothelial Cell Loss in Glaucoma and Glaucoma Surgery and the Utility of Management with Descemet Membrane Endothelial Keratoplasty (DMEK) ' , Journal of Ophthalmology , vol. 2022 , 1315299 . https://doi.org/10.1155/2022/1315299 |
Abstract: | The corneal endothelium has a crucial role in maintaining a clear and healthy cornea. Corneal endothelial cell loss occurs naturally with age; however, a diagnosis of glaucoma and surgical intervention for glaucoma can exacerbate a decline in cell number and impairment in morphology. In glaucoma, the mechanisms for this are not well understood and this accelerated cell loss can result in corneal decompensation. Given the high prevalence of glaucoma worldwide, this review aims to explore the abnormalities observed in the corneal endothelium in differing glaucoma phenotypes and glaucoma therapies (medical or surgical including with new generation microinvasive glaucoma surgeries). Descemet membrane endothelial keratoplasty (DMEK) is increasingly being used to manage corneal endothelial failure for glaucoma patients and we aim to review the recent literature evaluating the use of this technique in this clinical scenario. |
Description: | Publisher Copyright: © 2022 Neeru A Vallabh et al. |
DOI: | 10.1155/2022/1315299 |
ISSN: | 2090-004X |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
File | Size | Format | |
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Corneal_Endothelial_Cell_Loss_in_Glaucoma_and_Glaucoma_Surgery.pdf | 1.05 MB | Adobe PDF | View/Open |
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