Corneal Endothelial Cell Loss in Glaucoma and Glaucoma Surgery and the Utility of Management with Descemet Membrane Endothelial Keratoplasty (DMEK)

dc.contributor.authorVallabh, Neeru A.
dc.contributor.authorKennedy, Stephnie
dc.contributor.authorVinciguerra, Riccardo
dc.contributor.authorMcLean, Keri
dc.contributor.authorLevis, Hannah
dc.contributor.authorBorroni, Davide
dc.contributor.authorRomano, Vito
dc.contributor.authorWilloughby, Colin E.
dc.contributor.institutionDepartment of Doctoral Studies
dc.date.accessioned2023-02-27T10:10:01Z
dc.date.available2023-02-27T10:10:01Z
dc.date.issued2022
dc.descriptionPublisher Copyright: © 2022 Neeru A Vallabh et al.
dc.description.abstractThe corneal endothelium has a crucial role in maintaining a clear and healthy cornea. Corneal endothelial cell loss occurs naturally with age; however, a diagnosis of glaucoma and surgical intervention for glaucoma can exacerbate a decline in cell number and impairment in morphology. In glaucoma, the mechanisms for this are not well understood and this accelerated cell loss can result in corneal decompensation. Given the high prevalence of glaucoma worldwide, this review aims to explore the abnormalities observed in the corneal endothelium in differing glaucoma phenotypes and glaucoma therapies (medical or surgical including with new generation microinvasive glaucoma surgeries). Descemet membrane endothelial keratoplasty (DMEK) is increasingly being used to manage corneal endothelial failure for glaucoma patients and we aim to review the recent literature evaluating the use of this technique in this clinical scenario.en
dc.description.statusPeer reviewed
dc.format.extent1076941
dc.identifier.citationVallabh, N A, Kennedy, S, Vinciguerra, R, McLean, K, Levis, H, Borroni, D, Romano, V & Willoughby, C E 2022, 'Corneal Endothelial Cell Loss in Glaucoma and Glaucoma Surgery and the Utility of Management with Descemet Membrane Endothelial Keratoplasty (DMEK)', Journal of Ophthalmology, vol. 2022, 1315299. https://doi.org/10.1155/2022/1315299
dc.identifier.doi10.1155/2022/1315299
dc.identifier.issn2090-004X
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/10647
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85131156176&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofJournal of Ophthalmology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectOphthalmology
dc.titleCorneal Endothelial Cell Loss in Glaucoma and Glaucoma Surgery and the Utility of Management with Descemet Membrane Endothelial Keratoplasty (DMEK)en
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/systematicreview

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Corneal_Endothelial_Cell_Loss_in_Glaucoma_and_Glaucoma_Surgery.pdf
Size:
1.03 MB
Format:
Adobe Portable Document Format