Please use this identifier to cite or link to this item:
10.3390/medicina59020340
| Title: | Opportunities of Amlodipine as a Potential Candidate in the Evaluation of Drug Compliance during Antihypertensive Therapy |
| Authors: | Kustovs, Dmitrijs Urtāne, Inga Sevostjanovs, Eduards Moreino, Eva Trušinskis, Kārlis Department of Pharmaceutical Chemistry Department of Internal Diseases |
| Keywords: | amlodipine;adherence;drug monitoring;dehydro-amlodipine;hypertension;3.2 Clinical medicine;3.1 Basic medicine;1.1. Scientific article indexed in Web of Science and/or Scopus database |
| Issue Date: | 10-Feb-2023 |
| Citation: | Kustovs , D , Urtāne , I , Sevostjanovs , E , Moreino , E & Trušinskis , K 2023 , ' Opportunities of Amlodipine as a Potential Candidate in the Evaluation of Drug Compliance during Antihypertensive Therapy ' , Medicina , vol. 59 , no. 2 , 340 . https://doi.org/10.3390/medicina59020340 |
| Abstract: | Background and Objectives: Blood pressure measurement is essential evidence to establish that the chosen medicine and dosage are appropriate, and also indirectly indicates whether the medicine is being used at all. Therefore, current research compares adherence to the target blood pressure at home and in the hospital between different age groups, using similar combinations of the drugs prescribed by the doctor within ongoing antihypertensive therapy. Moreover, it is very important to develop a method for the determination of amlodipine and its metabolite, which would suitable for clinical applications, when the result is needed as quick as possible. Materials and Methods: This prospective study included patients aged ≥18 years who were diagnosed with hypertension. Subjects were divided into two age groups according to European Society of Cardiology (ESC) hypertension guidelines; older patients (≥65 years) and adult patients ( |
| Description: | Funding Information: The present study was part of the doctoral research program. The current doctoral research project was funded by the Riga Stradiņš University (Nr. 6-ZD-22/15/2021). The funder had no role in the design and conduct of the study; the collection, management, analysis, and interpretation of the data; and the preparation, review, or approval of the manuscript. Publisher Copyright: © 2023 by the authors. |
| DOI: | 10.3390/medicina59020340 |
| ISSN: | 1010-660X |
| Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
| File | Size | Format | |
|---|---|---|---|
| Opportunities_of_Amlodipine.pdf | 3.18 MB | Adobe PDF | View/Open |
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