Please use this identifier to cite or link to this item:
10.3390/polym14235068
| Title: | Design, Fabrication, and Application of Mini-Scaffolds for Cell Components in Tissue Engineering |
| Authors: | Mironov, Vladimir A. Senatov, Fedor S. Koudan, Elizaveta V. Pereira, Frederico D.A.S. Kasyanov, Vladimir A. Granjeiro, Jose Mauro Baptista, Leandra Santos Joint Laboratory of Traumatology and Orthopaedics |
| Keywords: | functionalization;mini-scaffolds;synergistic approach;tissue spheroids;1.4 Chemical sciences;2.5 Materials engineering;1.1. Scientific article indexed in Web of Science and/or Scopus database;General Chemistry;Polymers and Plastics;SDG 3 - Good Health and Well-being |
| Issue Date: | Dec-2022 |
| Citation: | Mironov , V A , Senatov , F S , Koudan , E V , Pereira , F D A S , Kasyanov , V A , Granjeiro , J M & Baptista , L S 2022 , ' Design, Fabrication, and Application of Mini-Scaffolds for Cell Components in Tissue Engineering ' , Polymers , vol. 14 , no. 23 , 5068 . https://doi.org/10.3390/polym14235068 |
| Abstract: | The concept of “lockyballs” or interlockable mini-scaffolds fabricated by two-photon polymerization from biodegradable polymers for the encagement of tissue spheroids and their delivery into the desired location in the human body has been recently introduced. In order to improve control of delivery, positioning, and assembly of mini-scaffolds with tissue spheroids inside, they must be functionalized. This review describes the design, fabrication, and functionalization of mini-scaffolds as well as perspectives on their application in tissue engineering for precisely controlled cell and mini-tissue delivery and patterning. The development of functionalized mini-scaffolds advances the original concept of “lockyballs” and opens exciting new prospectives for mini-scaffolds’ applications in tissue engineering and regenerative medicine and their eventual clinical translation. |
| Description: | Funding Information: This research was funded by the Ministry of Science and Higher Education of the Russian Federation under the strategic academic Not acceptable leadership program “Priority 2030”. Publisher Copyright: © 2022 by the authors. |
| DOI: | 10.3390/polym14235068 |
| ISSN: | 2073-4360 |
| Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
| File | Size | Format | |
|---|---|---|---|
| Design_Fabrication_and_Application_of_Mini_Scaffolds.pdf | 3.43 MB | Adobe PDF | View/Open |
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