Less is more : new one-step intracameral chemotherapy technique
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Date
2021
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Abstract
Purpose: To describe the feasibility of a new one-step approach to aspirate the aqueous and apply melphalan in a single-go without repeated entries into the anterior chamber. Methods: This retrospective non-comparative study was conducted at a referral center and included 12 patients. The one-step approach is described in a step-wise manner. No complications were observed among the patients. Results: One single injection of intracameral melphalan proved to be a successful treatment in nine cases. Two patients required a second injection, which was administered two weeks after the first one following the same technique. Conclusions: This proved to be a reasonable technique for the smooth application of melphalan in the anterior chamber studded with retinoblastoma seeds. Our outcomes revealed that it is an effective, quick, and cost-effective technique. Longer-term data collection is underway, though initial findings are encouraging.
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© The Authors.Romanian Society of Ophthalmology.
Keywords
Antineoplastic Agents, Alkylating/therapeutic use, Humans, Infant, Melphalan, Retinal Neoplasms, Retinoblastoma, Retrospective Studies, 3.2 Clinical medicine, 1.1. Scientific article indexed in Web of Science and/or Scopus database
Citation
Borroni, D, Bonzano, C, Rachwani-Anil, R, Rocha-de Lossada, C, Martín, F Z, Garcia-Lorente, M, Bonzano, E & Khaqan, H A 2021, 'Less is more : new one-step intracameral chemotherapy technique', Romanian journal of ophthalmology, vol. 65, no. 3, pp. 218-221. https://doi.org/10.22336/rjo.2021.44