Please use this identifier to cite or link to this item:
10.1111/j.1745-7262.2006.00112.x
| Title: | Sperm chromatin structure and male fertility : biological and clinical aspects |
| Authors: | Erenpreiss, Juris Spano, M. Erenpreisa, J. Bungum, M. Giwercman, A. |
| Keywords: | Damage;DNA;Human;Infertility;Sperm;3.1 Basic medicine;3.2 Clinical medicine;1.1. Scientific article indexed in Web of Science and/or Scopus database;Urology;SDG 3 - Good Health and Well-being |
| Issue Date: | Jan-2006 |
| Citation: | Erenpreiss , J , Spano , M , Erenpreisa , J , Bungum , M & Giwercman , A 2006 , ' Sperm chromatin structure and male fertility : biological and clinical aspects ' , Asian Journal of Andrology , vol. 8 , no. 1 , pp. 11-29 . https://doi.org/10.1111/j.1745-7262.2006.00112.x |
| Abstract: | Aim: Sperm chromatin/DNA integrity is essential for the accurate transmission of paternal genetic information, and normal sperm chromatin structure is important for sperm fertilizing ability. The routine examination of semen, which includes sperm concentration, motility and morphology, does not identify defects in sperm chromatin structure. The origin of sperm DNA damage and a variety of methods for its assessment are described. Evaluation of sperm DNA damage appears to be a useful tool for assessing male fertility potential both in vivo and in vitro. The possible impact of sperm DNA defects on the offspring is also discussed. |
| DOI: | 10.1111/j.1745-7262.2006.00112.x |
| ISSN: | 1008-682X |
| Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
| File | Size | Format | |
|---|---|---|---|
| Sperm_chromatin_structure_and_male_fertility.pdf | 448.18 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.