Please use this identifier to cite or link to this item:
10.2174/1874226201909010001
Title: | Biomarkers of Multiple Sclerosis |
Authors: | Pastare, Daina Bennour, Mohamed Ridha Polunosika, Elīna Karelis, Guntis Department of Neurology and Neurosurgery Department of Infectology |
Keywords: | Multiple sclerosis;Imaging;Genetic-immunogenetic;Biomarkers;Magnetic resonance;Laboratory;3.2 Clinical medicine;1.4. Reviewed scientific article published in Latvia or abroad in a scientific journal with an editorial board (including university editions) |
Issue Date: | 2019 |
Citation: | Pastare , D , Bennour , M R , Polunosika , E & Karelis , G 2019 , ' Biomarkers of Multiple Sclerosis ' , The Open Immunology Journal , vol. 9 , pp. 1-13 . https://doi.org/10.2174/1874226201909010001 |
Abstract: | The search for an ideal multiple sclerosis biomarker with good diagnostic value, prognostic reference and an impact on clinical outcome has yet to be realized and is still ongoing. The aim of this review is to establish an overview of the frequent biomarkers for multiple sclerosis that exist to date. The review summarizes the results obtained from electronic databases, as well as thorough manual searches. In this review the sources and methods of biomarkers extraction are described; in addition to the description of each biomarker, determination of the prognostic, diagnostic, disease monitoring and treatment response values besides clinical impact they might possess. We divided the biomarkers into three categories according to the achievement method: laboratory markers, genetic-immunogenetic markers and imaging markers. We have found two biomarkers at the time being considered the gold standard for MS diagnostics. Unfortunately, there does not exist a single solitary marker being able to present reliable diagnostic value, prognostic value, high sensitivity and specificity as well as clinical impact. We need more studies to find the best biomarker for MS. |
DOI: | 10.2174/1874226201909010001 |
ISSN: | 1874-2262 |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
File | Size | Format | |
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Biomarkers_of_Multiple_Sclerosis.pdf | 313.49 kB | Adobe PDF | View/Open |
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