Please use this identifier to cite or link to this item:
10.3390/molecules16098041
| Title: | Intramolecular C-H⋯O hydrogen bonding in 1,4-dihydropyridine derivatives |
| Authors: | Petrova, Marina Muhamadejev, Ruslan Vigante, Brigita Cekavicus, Brigita Plotniece, Aiva Duburs, Gunars Liepinsh, Edvards |
| Keywords: | 1,4-dihydropyridines;Bromination;Hydrogen bond;NMR spectra;Nucleophilic substitution;Quantum chemical calculations;1.4 Chemical sciences;1.6 Biological sciences;3.1 Basic medicine;1.1. Scientific article indexed in Web of Science and/or Scopus database;Analytical Chemistry;Chemistry (miscellaneous);Molecular Medicine;Pharmaceutical Science;Drug Discovery;Physical and Theoretical Chemistry;Organic Chemistry |
| Issue Date: | Sep-2011 |
| Citation: | Petrova , M , Muhamadejev , R , Vigante , B , Cekavicus , B , Plotniece , A , Duburs , G & Liepinsh , E 2011 , ' Intramolecular C-H⋯O hydrogen bonding in 1,4-dihydropyridine derivatives ' , Molecules , vol. 16 , no. 9 , pp. 8041-8052 . https://doi.org/10.3390/molecules16098041 |
| Abstract: | The diastereotopy of the methylene protons at positions 2 and 6 in 1,4-dihydropiridine derivatives with various substituents has been investigated. NMR spectroscopy and quantum chemistry calculations show that the CH⋯O intramolecular hydrogen bond is one of the factors amplifying the chemical shift differences in the 1H-NMR spectra. |
| DOI: | 10.3390/molecules16098041 |
| ISSN: | 1420-3049 |
| Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
| File | Size | Format | |
|---|---|---|---|
| Intramolecular_C_H_O_Hydrogen_Bonding.pdf | 562.3 kB | Adobe PDF | View/Open |
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