Please use this identifier to cite or link to this item:
10.31288/oftalmolzh202425256
Title: | Acute retinal pigment epitheliitis and dosimetric follow-up : a case report |
Authors: | Babenko, Tetiana Fedirko, Pavlo Saksonov, Stanislav Shevchenko, Iryna Pilmane, Māra Vasylenko, Valentyna Korobova, Oleksandra Garkava, Natalia Mykola, Kuriata Institute of Anatomy and Anthropology |
Keywords: | acute retinal pigment epitheliitis;ionizing radiation;macula;retina;optical coherence tomography;morphological changes;incorporation of radioactive isotopes;whole-body counter;3.1 Basic medicine;3.2 Clinical medicine;1.4. Reviewed scientific article published in Latvia or abroad in a scientific journal with an editorial board (including university editions) |
Issue Date: | 1-May-2024 |
Citation: | Babenko , T , Fedirko , P , Saksonov , S , Shevchenko , I , Pilmane , M , Vasylenko , V , Korobova , O , Garkava , N & Mykola , K 2024 , ' Acute retinal pigment epitheliitis and dosimetric follow-up : a case report ' , Oftalmologicheskii Zhurnal , no. 2 , pp. 52-56 . https://doi.org/10.31288/oftalmolzh202425256 |
Abstract: | Acute retinal pigment epitheliitis (ARPE; also known as Krill disease), a disease first described in the nineteen seventies, is characterized by fine pigment stippling in the macular area, surrounded by hypopigmented halo. The etiology of the disease is not yet known. The patient reported that he used to eat berries picked from the forest in the radioactive contaminated area in late June to early July, 2023. He complained of transient metamorphopsia and reduced vision in the left eye, and received eye examination including optical coherence tomography, general check-up, blood cell counts and whole body radionuclide content study. He was diagnosed with bilateral APRE. On the basis of measurements with the expert whole-body counter, the wholebody burden of Сs-137 for the patient was 505 Bq, and the estimated annual effective dose from internal radiation was 0.011 mSv/y. The estimated dose value was substantially lower than the basic dose limit for the population of 1 mSv/y as per requirement of the Law of Ukraine. Because APRE is a rare disease with an unknown etiology, careful attention deserves to be given to the finding of the disease in a patient who has sustained short-term exposure to ionizing radiation due to the incorporation of Сs-137 into his body tissues. For the first time it has become possible to assess adequately doses from internal radiation in a patient with APRE, which will allow to optimize efforts for further research on the etiology of this rare disorder. |
DOI: | 10.31288/oftalmolzh202425256 |
ISSN: | 0030-0675 |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
Files in This Item:
File | Size | Format | |
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Acute_retinal_pigment_epitheliitis.pdf | 1.95 MB | Adobe PDF | View/Open |
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