Please use this identifier to cite or link to this item:
10.3390/medicina60040568
Title: | The Initial Experience of Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension in Latvia |
Authors: | Krigere, Anna Kalejs, Verners Roberts Kaulins, Ricards Rudzitis, Ainars Bondare, Līga Sablinskis, Matiss Lejnieks, Aivars Kigitovica, Dana Kurzyna, Marcin Skride, Andris Department of Internal Diseases |
Keywords: | Latvia;balloon pulmonary angioplasty;chronic thromboembolic pulmonary hypertension;3.2 Clinical medicine;1.1. Scientific article indexed in Web of Science and/or Scopus database;General Medicine |
Issue Date: | 30-Mar-2024 |
Citation: | Krigere , A , Kalejs , V R , Kaulins , R , Rudzitis , A , Bondare , L , Sablinskis , M , Lejnieks , A , Kigitovica , D , Kurzyna , M & Skride , A 2024 , ' The Initial Experience of Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension in Latvia ' , Medicina (Kaunas) , vol. 60 , no. 4 , 568 . https://doi.org/10.3390/medicina60040568 |
Abstract: | Background: Treatment options for inoperable chronic thromboembolic pulmonary hypertension (CTEPH) or persistent pulmonary hypertension after pulmonary endarterectomy (PEA) include targeted medical therapy and balloon pulmonary angioplasty (BPA). BPA is an emerging treatment modality that has been reported to improve functional capacity, pulmonary hemodynamics, and right ventricular function. Reports from expert centers are promising, but more data are needed to make the results more generalizable. Materials and Methods: We conducted a prospective analysis of nine consecutive CTEPH patients who underwent balloon pulmonary angioplasty (BPA) sessions at Pauls Stradins Clinical University Hospital in Riga, Latvia between 1 April 2022 and 1 July 2023. We assessed World Health Organization (WHO) functional class, 6 min walk distance (6MWD), blood oxygen saturation (SpO2), brain natriuretic peptide (BNP) level at baseline and 3 months after the first BPA session. For two patients on whom repeated BPA sessions were performed, we additionally assessed cardiac output (CO), pulmonary vascular resistance (PVR), and mean pulmonary artery pressure (mPAP). Results: A total of 12 BPA procedures for nine patients were performed; repeated BPA sessions were performed for two patients. Our results show a reduction in BNP levels and improvement in WHO functional class, 6MWD, and SpO2 after the first BPA session. Improvement in 6MWD was statistically significant. Additionally, an improvement in pulmonary hemodynamic parameters was observed. Conclusions: Our data show that BPA is an effective interventional treatment modality, improving both the pulmonary hemodynamics and functional status. Moreover, BPA is safe and excellently tolerated. |
Description: | Publisher Copyright: © 2024 by the authors. |
DOI: | 10.3390/medicina60040568 |
ISSN: | 1010-660X |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
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