Cell proliferation and apoptosis in wistar rat kidney after renal mass ablation and low-dose irradiation

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dc.contributor.authorAunapuu, Marina
dc.contributor.authorArend, Andres
dc.contributor.authorOts, Mai
dc.contributor.authorPilmane, Mara
dc.contributor.institutionInstitute of Anatomy and Anthropology
dc.date.accessioned2021-04-28T08:25:01Z
dc.date.available2021-04-28T08:25:01Z
dc.date.issued2010
dc.description.abstractCell proliferation and apoptosis in the remnant rat kidney after treatment with lowdose irradiation was investigated. Material and methods. In the first group (n=9), adult male Wistar rats underwent 5/6 nephrectomy (NPX); in the second group (n=9), NPX was combined with low-dose irradiation. Rats without surgery and irradiation formed the control group (n=9). Results. Hypertension and proteinuria induced by NPX were decreased by 3-Gy irradiation. The 5/6 NPX rats showed a dramatic increase in proliferating and apoptotic cells in the glomeruli and in the distal tubules at week 2, which was significantly decreased by low-dose irradiation. Conclusion. The data demonstrate that low-dose irradiation is a factor slowing the process of chronic renal injury.en
dc.description.statusPeer reviewed
dc.format.extent7
dc.format.extent259016
dc.identifier.citationAunapuu, M, Arend, A, Ots, M & Pilmane, M 2010, 'Cell proliferation and apoptosis in wistar rat kidney after renal mass ablation and low-dose irradiation', Medicina, vol. 46, no. 3, pp. 204-210. https://doi.org/10.3390/medicina46030029
dc.identifier.doi10.3390/medicina46030029
dc.identifier.issn1010-660X
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/3952
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=77954500971&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofMedicina
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectApoptosis
dc.subjectCell proliferation
dc.subjectLow-dose radiation
dc.subjectRat
dc.subjectRemnant kidney
dc.subject3.1 Basic medicine
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectGeneral Medicine
dc.titleCell proliferation and apoptosis in wistar rat kidney after renal mass ablation and low-dose irradiationen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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