Ārstniecisko augu bolusu cukura diabēta slimniekiem izstrāde.
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Date
2020
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Rīgas Stradiņa universitāte
Rīga Stradiņš University
Rīga Stradiņš University
Abstract
Paaugstināts glikozes līmenis asinīs vai cukura diabēts ir diezgan bieža slimība, īpaši II tipa diabēts. Ar katru gadu slimnieku skaits tikai pieaug.
Lai palīdzētu uzlabot II tipa cukura diabēta slimnieku stāvokli, tika izstrādāts uz antidiabētiskas tējas bāzes uztura bagātinātājs košļājamu bolusu veidā. Tas ir ārstniecisko augu maisījums, kas tika samaisīts ar lipīgu saistvielas masu un noformēta sfērās.
Lipīga masa, kas satur visas sausās vielas kopā, ir maltas kaltētas dzērvenes. Lai zinātu cik daudz vajag šīs masas tika veikti eksperimentāli pārbaudījumi. Laboratorijas paraugu - bolusu veidošana tika veikta ar rokām, pēc tam receptūra tika pārbaudīta rūpnieciski ražojot bolusus.
Rezultātā tika izstrādāta receptūra, kas ļauj rūpnieciski ražot bolusus. Receptūrā ietilpst: mellenes vasa (Vaccinium myrtillus), rasaskrēsliņa laksti (Alchemilla vulgaris), upenes lapas (Ribes nigrum), brūklenes lapas (Vaccinium vitis-idaea), pupiņas pākstenis (Phaseolus vulgaris), tīruma kosas laksti (Equisetum arvense), pienenes saknes (Taraxacum officinale), nātrenes lapas (Urtica dioica), ālantes saknes (Inula helenium), piparmētru lapas (Mentha piperita), smiltsērkšķu lapas (Hippophaё rhamnoides), čagas ekstrakts (Inonotus obliquus), kviešu klijas, kviešu šķiedrvielas, kaltētas dzērvenes, kanēlis, ingvers, krustnagliņas, koncentrēta ābolu sula, kālija sorbāts un nātrija benzoāts. Cukuru daudzums vienā bolusā ir 3,40 g, tas ir daudz, tomēr, liela daļa izejvielu bolusā ir ar cukura līmeņa pazeminošu darbību un sastāvdaļas ir no dabīgiem produktiem, bez cukura pievienošanas. Bolusi ir ar patīkamu garšu un viegli košļājami.
Ir vēlams veikt efektivitātes un drošuma pārbaudes, kā arī produkta stabilitātes izpēti. Pašlaik tiek pabeigta receptūras izstrāde, un, kad Inovatīvo biomedicīnas tehnoloģiju institūta darbinieki būs pārliecināti par produkta kvalitāti, bolusi tiks ražoti rūpnieciski.
High blood sugar or diabetes mellitus is a fairly common disease, especially type II diabetes. The number of patients is only increasing every year. To help improve the condition of patients with type 2 diabetes, an antidiabetic tea-based food supplement in the form of chewing boluses was developed. It is a mixture of herbs that was mixed with a sticky binder mass and formed into spheres. The sticky mass that holds all the dry raw material together is a dried cranberries. Experimental tests were performed to know how much this mass was needed. The formation of laboratory samples - boluses was formed by hand, then the recipe was tested during industrial production of boluses. As a result, a recipe was developed that allows the industrial production of boluses. The recipe includes: blueberry vase (Vaccinium myrtillus), Lady’s-mantle top (Alchemilla vulgaris), blackcurrant leaves (Ribes nigrum), lingonberry leaves (Vaccinium vitis-idaea), bean pod (Phaseolus vulgaris), field Horsetail top (Equisetum arvense), dandelion roots (Taraxacum officinale), nettle leaves (Urtica dioica), elecampane roots (Inula helenium), mint leaves (Mentha piperita), Sea-buckthorn leaves (Hippophaё rhamnoides), chaga extract (Inonotus obliquus), wheat bran, wheat fiber, dried cranberries, ginger, cloves, concentrated apple juice, potassium sorbate and sodium benzoate. The amount of sugar in one bolus is 3.40 g, which is a lot, however, a large part of the raw materials in the bolus have a sugar-lowering effect and the ingredients are from natural products, without the addition of sugar. Boluses have a pleasant taste and are easy to chew. Efficacy and safety tests as well as product stability studies are desirable. The development of the recipe is currently being completed, and when the staff of the Institute of Innovative Biomedical Technologies is convinced of the quality of the product, it will be transferred to industrial production.
High blood sugar or diabetes mellitus is a fairly common disease, especially type II diabetes. The number of patients is only increasing every year. To help improve the condition of patients with type 2 diabetes, an antidiabetic tea-based food supplement in the form of chewing boluses was developed. It is a mixture of herbs that was mixed with a sticky binder mass and formed into spheres. The sticky mass that holds all the dry raw material together is a dried cranberries. Experimental tests were performed to know how much this mass was needed. The formation of laboratory samples - boluses was formed by hand, then the recipe was tested during industrial production of boluses. As a result, a recipe was developed that allows the industrial production of boluses. The recipe includes: blueberry vase (Vaccinium myrtillus), Lady’s-mantle top (Alchemilla vulgaris), blackcurrant leaves (Ribes nigrum), lingonberry leaves (Vaccinium vitis-idaea), bean pod (Phaseolus vulgaris), field Horsetail top (Equisetum arvense), dandelion roots (Taraxacum officinale), nettle leaves (Urtica dioica), elecampane roots (Inula helenium), mint leaves (Mentha piperita), Sea-buckthorn leaves (Hippophaё rhamnoides), chaga extract (Inonotus obliquus), wheat bran, wheat fiber, dried cranberries, ginger, cloves, concentrated apple juice, potassium sorbate and sodium benzoate. The amount of sugar in one bolus is 3.40 g, which is a lot, however, a large part of the raw materials in the bolus have a sugar-lowering effect and the ingredients are from natural products, without the addition of sugar. Boluses have a pleasant taste and are easy to chew. Efficacy and safety tests as well as product stability studies are desirable. The development of the recipe is currently being completed, and when the staff of the Institute of Innovative Biomedical Technologies is convinced of the quality of the product, it will be transferred to industrial production.
Description
Farmācija
Pharmacy
Veselības aprūpe
Health Care
Pharmacy
Veselības aprūpe
Health Care
Keywords
cukura diabēts, boluss, uztura bagātinātāju izstrāde., diabetes mellitus, bolus, development of food supplements., Vaccinium myrtillus, Alchemilla vulgaris, Ribes nigrum, Vaccinium vitis-idaea, Phaseolus vulgaris, Equisetum arvense, Taraxacum officinale, Urtica dioica, Inula helenium, Mentha piperita, Hippophaё rhamnoides, Inonotus obliquus.