Mercury Exposure & Cardiovascular Diseases
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Rīgas Stradiņa universitāte
Rīga Stradiņš University
Rīga Stradiņš University
Kopsavilkums
Šajā literatūras pārskatā tiek izklāstīta sarežģītā saistība starp dzīvsudrabu ekspozīciju un kardiovaskulārajām slimībām (KVS). Tas izskaidro, kā cilvēki ir pakļauti dzīvsudrabam caur dažādām avotiem, piemēram, piesārņotu zivju, zobu amalgāmu pildījumiem un rūpnieciskiem izmešiem, īpaši metilēdzīvsudraba veidā. Pārskats uzsver metilēdzīvsudrabu kā galveno ieguldītāju KVS attīstībā, aktivizējot vairākus kardiogēnus mehānismus, tostarp oksidatīvo stresu, iekaisumu, endotēlija disfunkciju un dislipidēmiju. Turklāt tas akcentē dzīvsudraba ekspozīcijas plašo izplatību, kas bieži notiek nejauši, uzsverot nepieciešamību pēc paaugstinātas informētības un agrīnas slimības atklāšanas un skrīninga nozīmi.
Pētījuma mērķis ir piedāvāt vispusīgu izpratni par dzīvsudrabu ekspozīcijas avotiem, tā ietekmi uz cilvēku veselību, īpaši kardiovaskulāro sistēmu, un sekojošajiem bojājumiem. Turklāt tas apspriež valdības un organizāciju intervences, kas vērstas uz dzīvsudraba ekspozīcijas mazināšanu.
Metodoloģija ietver rūpīgu esošās literatūras pārskatu, kas iegūts no datu bāzēm, piemēram, PubMed, Web of Science un Google Scholar, kā arī no valdības aģentūrām un departamentiem. Relevants raksti, pētījumu dokumenti un ziņojumi tika izvērtēti, lai apkopotu informāciju par dzīvsudraba ekspozīciju, KVS, vides noteikumiem un profilakses pasākumiem.
Secinājumā pārskats uzsver dzīvsudraba nopietnos veselības riskus, akcentējot tā kaitīgo ietekmi ne tikai uz kardiovaskulāro sistēmu, bet arī uz citiem orgāniem un sistēmisko cirkulāciju. Tas aicina uz paaugstinātu informētību, turpmākiem pētījumiem un turpmākām studijām šajā būtiskajā jomā.
This literature review delves into the intricate relationship between mercury exposure and cardiovascular diseases (CVDs). It elucidates how humans are susceptible to mercury through various sources such as contaminated fish, dental amalgam fillings, and industrial emissions, particularly in the form of methylmercury. The review highlights methylmercury as a primary contributor to the development of CVDs by triggering multiple cardiogenic mechanisms including oxidative stress, inflammation, endothelial dysfunction, and dyslipidemia. Moreover, it underscores the alarming prevalence of mercury exposure, often occurring inadvertently, underscoring the critical need for heightened awareness and the importance of early detection and screening of associated diseases. The study's aim is to offer a comprehensive understanding of mercury exposure sources, its effects on human health, particularly the cardiovascular system, and the ensuing damages. Furthermore, it discusses governmental and organizational interventions aimed at mitigating mercury exposure. The methodology involves a meticulous review of existing literature sourced from databases like PubMed, Web of Science, and Google Scholar, as well as government agencies and departments. Relevant articles, research papers, and reports were scrutinized to gather insights into mercury exposure, CVDs, environmental regulations, and preventive measures. In conclusion, the review underscores the grave health risks posed by mercury, emphasizing its detrimental effects not only on the cardiovascular system but also on other organs and systemic circulation. It advocates for heightened awareness, further research, and continued studies in this critical area.
This literature review delves into the intricate relationship between mercury exposure and cardiovascular diseases (CVDs). It elucidates how humans are susceptible to mercury through various sources such as contaminated fish, dental amalgam fillings, and industrial emissions, particularly in the form of methylmercury. The review highlights methylmercury as a primary contributor to the development of CVDs by triggering multiple cardiogenic mechanisms including oxidative stress, inflammation, endothelial dysfunction, and dyslipidemia. Moreover, it underscores the alarming prevalence of mercury exposure, often occurring inadvertently, underscoring the critical need for heightened awareness and the importance of early detection and screening of associated diseases. The study's aim is to offer a comprehensive understanding of mercury exposure sources, its effects on human health, particularly the cardiovascular system, and the ensuing damages. Furthermore, it discusses governmental and organizational interventions aimed at mitigating mercury exposure. The methodology involves a meticulous review of existing literature sourced from databases like PubMed, Web of Science, and Google Scholar, as well as government agencies and departments. Relevant articles, research papers, and reports were scrutinized to gather insights into mercury exposure, CVDs, environmental regulations, and preventive measures. In conclusion, the review underscores the grave health risks posed by mercury, emphasizing its detrimental effects not only on the cardiovascular system but also on other organs and systemic circulation. It advocates for heightened awareness, further research, and continued studies in this critical area.
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Medicīna
Medicine
Veselības aprūpe
Health Care
Medicine
Veselības aprūpe
Health Care
Atslēgas vārdi
Dzīvsudraba ekspozīcija, Kardiovaskulārās slimības (KVS), Metilēdzīvsudrabs, Piesārņoto zivju patēriņš, Zobu amalgāma pildījumi, Rūpnieciskie avoti, Oksidatīvais stres, Iekaisums, Endotēlija disfunkcija, Dislipidēmija, Agrīna atklāšana, Valdības iejaukšanās, Profilaktiskie pasākumi, Mercury exposure, Cardiovascular diseases(CVDs), Methylmercury, Contaminated fish consumption, Dental amalgam fillings, Industrial sources, Oxidative stress, Inflammation, Endothelial dysfunction, Dyslipidemia, Early detection, Government interventions, Preventive measures.