Vērmeles ekstraktu antibakteriālā efektivitāte pret liellopu mastīta izraisītājiem.
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Date
2021
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Journal Title
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Rīgas Stradiņa universitāte
Rīga Stradiņš University
Rīga Stradiņš University
Abstract
Čulkstāne L., (2021) Vērmeles ekstraktu antibakteriālā efektivitāte pret liellopu mastīta izraisītājiem. Pētnieciskais darbs. Pētnieciskā darba vadītāja farmaceite Renāte Šukele. Rīgas Stradiņa universitāte. Darba pamatteksts sastāv no 24 lpp, 2 tab., 39 bibliogrāfijas nosaukumiem latviešu un angļu valodā.
Pēdējo gadu desmitu laikā augu izcelsmes produktu antibakteriālās īpašības ir piesaistījušas daudzus pētniekus, jo strauji palielinās antibiotiku rezistence pret mikroorganismiem un ir vajadzīga jaunu zāļu izstrāde. Vērmele ir asteru dzimtas augs, kura no seniem laikiem tiek plaši pielietota medicīnā tās saturošo bioloģiski aktīvo vielu dēļ. Kvalifikācijas darbā tiek apskatītas vērmeles ekstrakta bioloģiski aktīvās vielas, kādas ekstrakcijas metodes un šķīdinātāji tiek pielietoti, lai iegūtu kvalitatīvu auga ekstraktu, kādas ir antibakteriālās efektivitātes noteikšanas metodes. Veicot informācijas analīzi par vērmeles ekstraktu antibakteriālo efektivitāti secināms, ka vērmeles ekstrakts satur daudz bioloģiski aktīvas vielas, kas ir efektīvas gan pret vairākām gram - pozitīvām, gan gram - negatīvām baktērijām. Pētījuma mērķis ir noskaidrot, kuram vērmeles ekstraktam ir vislabākā antibakteriālā efektivitāte pret biežākajām mastītu izraisošām baktērijām, ekstrakta iegūšanai izmantojot 30%, 50%, 70% acetona šķīdumus un 30%, 50%, 70% etanola šķīdumus. Rezultātā varēja secināt, ka efektīvākie vērmeles ekstrakti ir iegūti ar 50%, 70% acetona un 70% etanola šķīdumiem.
Čulkstāne L., (2021) Antimicrobial activity of wormwood extracts against bovine mastitis isolates. Research paper. Mentor of the research paper - pharmacist Renate Šukele. Rīga Stradiņš University. Main content of the research paper consists of 24 pages, 2 tables, 39 bibliographic references in Latvian and English. In recent decades, antimicrobial properties of plant based products have attracted many researchers, as antibiotic resistance to microorganisms is rapidly increasing and there is an urgent need to develop new medicine products. Wormwood is an artemisian family plant, which is widely used in medicine because of the biologically active substances it contains. This qualification paper reviews, what are the biologically active substances of wormwood extract, which extraction methods and solvents are used to obtain a quality plant extract, and what antimicrobial efficiency detection methods there are. While carrying out an analysis of information on the antibacterial efficiency of wormwood extracts, it can be concluded that the wormwood extract contains many biologically active substances that are effective both against several gram-positive and gram-negative bacteria. Research aim is to find out which of the wormwood extracts has the best antibacterial efficiency against the most common mastitis causing bacteria, using 30%, 50%, 70% acetone solutions and 30%, 50%, 70% ethanol solutions for extraction. As a result, it was concluded that the most efficient wormwood extracts are obtained with 50%, 70% acetone and 70% ethanol solutions.
Čulkstāne L., (2021) Antimicrobial activity of wormwood extracts against bovine mastitis isolates. Research paper. Mentor of the research paper - pharmacist Renate Šukele. Rīga Stradiņš University. Main content of the research paper consists of 24 pages, 2 tables, 39 bibliographic references in Latvian and English. In recent decades, antimicrobial properties of plant based products have attracted many researchers, as antibiotic resistance to microorganisms is rapidly increasing and there is an urgent need to develop new medicine products. Wormwood is an artemisian family plant, which is widely used in medicine because of the biologically active substances it contains. This qualification paper reviews, what are the biologically active substances of wormwood extract, which extraction methods and solvents are used to obtain a quality plant extract, and what antimicrobial efficiency detection methods there are. While carrying out an analysis of information on the antibacterial efficiency of wormwood extracts, it can be concluded that the wormwood extract contains many biologically active substances that are effective both against several gram-positive and gram-negative bacteria. Research aim is to find out which of the wormwood extracts has the best antibacterial efficiency against the most common mastitis causing bacteria, using 30%, 50%, 70% acetone solutions and 30%, 50%, 70% ethanol solutions for extraction. As a result, it was concluded that the most efficient wormwood extracts are obtained with 50%, 70% acetone and 70% ethanol solutions.
Description
Farmācija
Pharmacy
Veselības aprūpe
Health Care
Pharmacy
Veselības aprūpe
Health Care
Keywords
Vērmeles ekstrakts. Antibakteriālā efektivitāte. Bioķīmiskais sastāvs. Antibakteriālās testēšanas metodes., Wormwood extract. Antibacterial efficiency. Biochemical composition. Antibacterial testing methods.