'Pretklepus sīrupa izstrāde pediatriskajai populācijas grupai.
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Date
2020
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Rīgas Stradiņa universitāte
Rīga Stradiņš University
Rīga Stradiņš University
Abstract
Tirgū ir pieejams mazs klasteris ar sīrupiem, kuri paredzēti klepum bērniem no 3 gadu vecuma un ir relatīvi droši, t.i. bez ķīmiskas dabas konservantiem, etilspirta, sintētiskajām saldinātājvielām, krāsvielām. Darba mērķis bija izstrādāt sīrupu, kurš ir paredzēts bērniem no 3 gadu vecuma un kura darbība tiek balstīta uz tradicionālo medicīnu un ilgstošas lietošanas pieredzi. Rezultātā darba mērķis bija sasniegts, sīrups ir izstrādāts ar vienkāršu sastāvu, bez ķīmiskas dabas konservantiem, etilspirta, sintētiskajām saldinātājvielām, krāsvielām. Kā galvenās palīgvielas tika izvēlētas – saharoze, kā sīrupa nesējviela un dabisks konservants, citronskābe, kā antioksidanta sinerģists un garšas uzlabotājs, askorbīnskābe, kā antioksidants. Stabilitātes pētījumi, lai noteiktu sīrupa derīguma termiņu un uzglabāšanas apstākļus, turpinās.
There is a small cluster of syrups available on the market for coughs in children from 3 years of age and is relatively safe, i.e. without chemical preservatives, ethyl alcohol, synthetic sweeteners, colorants. The aim of the study was to develop a syrup for children from 3 years old, based on traditional medicine and long-term experience. As a result, the aim of the work was achieved, the syrup is developed with a simple composition, without chemical preservatives, ethyl alcohol, synthetic sweeteners, colorants. The main excpients were choosen – sucrose as a syrup carrier and natural preservative, citric acid as an antioxidant synergist and flavor enhancer, ascorbic acid as an antioxidant. Stability studies to determine the shelf life and storage conditions of the syrup are ongoing.
There is a small cluster of syrups available on the market for coughs in children from 3 years of age and is relatively safe, i.e. without chemical preservatives, ethyl alcohol, synthetic sweeteners, colorants. The aim of the study was to develop a syrup for children from 3 years old, based on traditional medicine and long-term experience. As a result, the aim of the work was achieved, the syrup is developed with a simple composition, without chemical preservatives, ethyl alcohol, synthetic sweeteners, colorants. The main excpients were choosen – sucrose as a syrup carrier and natural preservative, citric acid as an antioxidant synergist and flavor enhancer, ascorbic acid as an antioxidant. Stability studies to determine the shelf life and storage conditions of the syrup are ongoing.
Description
Farmācija
Pharmacy
Veselības aprūpe
Health Care
Pharmacy
Veselības aprūpe
Health Care
Keywords
Pretklepus sīrups bērniem, klepus, atkrēpošana, ārstniecības alteja, šaurlapu ceļteka, vijīga efeja, osmotisks spiediens, saharoze, citronskābe, askorbīnskābe, devas un lietošanas biežums, ekstrakts, palīgvielas, stabilitāte., Antitussive syrup for children, cough, expectoration, therapeutic alto, narrow-leaved ryegrass, flexible ivy, osmotic pressure, sucrose, citric acid, ascorbic acid, child, dose and frequency of administration, extract, excipients, stability.