General influence of biphasic calcium phosphate on osteoporotic bone density

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dc.contributor.authorAnanjevs, Vladislavs
dc.contributor.authorAnanjeva, Aleksandra
dc.contributor.authorVetra, Janis
dc.contributor.authorSkagers, Andrejs
dc.contributor.authorSalma, Ilze
dc.contributor.authorNeimane, Laura
dc.contributor.authorKasyanov, Vladimir
dc.contributor.institutionDepartment of Oral and Maxillofacial Surgery and Oral Medicine
dc.contributor.institutionInstitute of Anatomy and Anthropology
dc.contributor.institutionBiomehānikas zinātniskā laboratorija
dc.date.accessioned2021-04-13T15:15:01Z
dc.date.available2021-04-13T15:15:01Z
dc.date.issued2019-05-01
dc.descriptionFunding Information: The study was supported by the National Research Programme No. 2014.10-4/VPP-3/21 “Multifunctional Components and composites, photonics and nanotechnology”. Project No. 4 “Nanocomponents and nanotechnologies for medical applications”. Publisher Copyright: © 2019 Vladislavs Ananjevs et al., published by Sciendo 2019. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.
dc.description.abstractBone density of the femur body of rabbit was determined in vivo. Experimental osteoporosis was induced by ovariectomy and subsequent injections of methylprednisolone. In the greater trochanter region of right femur, defects were created and filled with granules of hydroxyapatite and tricalcium phosphate (HAP/TCP 70/30) or HAP/TCP 70/30 together with 5% strontium. After three months, the animals were euthanized. The bone mass density of the right and left body of femur was measured by cone beam computed tomography (CT) scan. The results of the study showed that the right femur of the rabbit, where biomaterials had been implanted, and the left femur, where no biomaterial implantation occurred, became denser after filling the defect with HAP/TCP 70/30 ceramic granules or 5% Sr modified HAP/TCP ceramic granules. There was no difference between operated and non-operated legs and HAP/TCP and HAP/TCP with 5% strontium groups.en
dc.description.statusPeer reviewed
dc.format.extent4
dc.format.extent601426
dc.identifier.citationAnanjevs, V, Ananjeva, A, Vetra, J, Skagers, A, Salma, I, Neimane, L & Kasyanov, V 2019, 'General influence of biphasic calcium phosphate on osteoporotic bone density', Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences, vol. 73, no. 2, pp. 185-188. https://doi.org/10.2478/prolas-2019-0029
dc.identifier.doi10.2478/prolas-2019-0029
dc.identifier.issn1407-009X
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/3794
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85065676218&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofProceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectbiphasic calcium phosphate
dc.subjectbone density
dc.subjectin vivo
dc.subjectosteoporosis
dc.subjectstrontium
dc.subject3.2 Clinical medicine
dc.subject3.1 Basic medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectGeneral
dc.titleGeneral influence of biphasic calcium phosphate on osteoporotic bone densityen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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