Browsing by Author "Ananjevs, Vladislavs"

Now showing 1 - 2 of 2
  • No Thumbnail Available
    Item
    Calcium Phosphate Bioceramic Material Local Influence on the Bone Biomechanical Properties at Rabbits with Experimental Osteoporosis
    (2018) Ananjevs, Vladislavs; Ananjeva, Aleksandra; Vētra, Jānis; Skagers, Andrejs; Salma, Ilze; Ločs, Jānis; Kasyanov, Vladimir; Department of Oral and Maxillofacial Surgery and Oral Medicine; Institute of Anatomy and Anthropology; Biomehānikas zinātniskā laboratorija
    Biomechanical characteristicsof the rabbit cartilagecomponentfrom the femurwereinvestigated.The controlosteoporosishad beenactivatedby ovariectomy alongside theinjections of methylprednisolone. During the experiment defects in the femur’sgreater trochanter zonewas created andafterwardsfilled withthefragmentsof a hydroxyapatite as well astricalcium phosphate(HAP/TCP 70/30) or HAP/TCP 70/30mixedwith five percentstrontium. Threemonths lateranimals were euthanazed, squared samples werecut out from the femur’sbody andlatertested on a bend. The results ofthe research revealedthat the femurs becomemorestringentafter filling offdefects in the greater trochanter zonewith HAP/TCP 70/30or HAP/TCP 70/30mixed with fivepercentstrontium. The ultimate painfor the cartilagecomponentin the controlgroupswas less, than in thetest group.The flexure modulus of flexibilityof a cartilagecomponentin the test groupwas statistically reliable less, than the value of the flexure modulus of flexibilityof the cartilagecomponentin the controlgroups. Therefore, local usage ofcalcium –phosphatic bioceramic componentoverthe greater trochanter partincreasesbiomechanical characteristicsof the cartilagecomponentin the femurof animals.
  • No Thumbnail Available
    Item
    General influence of biphasic calcium phosphate on osteoporotic bone density
    (2019-05-01) Ananjevs, Vladislavs; Ananjeva, Aleksandra; Vetra, Janis; Skagers, Andrejs; Salma, Ilze; Neimane, Laura; Kasyanov, Vladimir; Department of Oral and Maxillofacial Surgery and Oral Medicine; Institute of Anatomy and Anthropology; Biomehānikas zinātniskā laboratorija
    Bone density of the femur body of rabbit was determined in vivo. Experimental osteoporosis was induced by ovariectomy and subsequent injections of methylprednisolone. In the greater trochanter region of right femur, defects were created and filled with granules of hydroxyapatite and tricalcium phosphate (HAP/TCP 70/30) or HAP/TCP 70/30 together with 5% strontium. After three months, the animals were euthanized. The bone mass density of the right and left body of femur was measured by cone beam computed tomography (CT) scan. The results of the study showed that the right femur of the rabbit, where biomaterials had been implanted, and the left femur, where no biomaterial implantation occurred, became denser after filling the defect with HAP/TCP 70/30 ceramic granules or 5% Sr modified HAP/TCP ceramic granules. There was no difference between operated and non-operated legs and HAP/TCP and HAP/TCP with 5% strontium groups.