Petrova, MarinaMuhamadejev, RuslanVigante, BrigitaCekavicus, BrigitaPlotniece, AivaDuburs, GunarsLiepinsh, Edvards2021-12-072021-12-072011-09Petrova, M, Muhamadejev, R, Vigante, B, Cekavicus, B, Plotniece, A, Duburs, G & Liepinsh, E 2011, 'Intramolecular C-H⋯O hydrogen bonding in 1,4-dihydropyridine derivatives', Molecules, vol. 16, no. 9, pp. 8041-8052. https://doi.org/10.3390/molecules160980411420-3049https://dspace.rsu.lv/jspui/handle/123456789/6979The diastereotopy of the methylene protons at positions 2 and 6 in 1,4-dihydropiridine derivatives with various substituents has been investigated. NMR spectroscopy and quantum chemistry calculations show that the CH⋯O intramolecular hydrogen bond is one of the factors amplifying the chemical shift differences in the 1H-NMR spectra.12575795enginfo:eu-repo/semantics/openAccess1,4-dihydropyridinesBrominationHydrogen bondNMR spectraNucleophilic substitutionQuantum chemical calculations1.4 Chemical sciences1.6 Biological sciences3.1 Basic medicine1.1. Scientific article indexed in Web of Science and/or Scopus databaseAnalytical ChemistryChemistry (miscellaneous)Molecular MedicinePharmaceutical ScienceDrug DiscoveryPhysical and Theoretical ChemistryOrganic Chemistry/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article10.3390/molecules16098041http://www.scopus.com/inward/record.url?scp=80053248957&partnerID=8YFLogxK