Kaļva, KalvisZdanovskis, NaurisŠneidere, KristīneKostiks, AndrejsKarelis, GuntisPlatkājis, ArdisStepens, Ainārs2024-01-102024-01-102023-12-16Kaļva, K, Zdanovskis, N, Šneidere, K, Kostiks, A, Karelis, G, Platkājis, A & Stepens, A 2023, 'Whole Brain and Corpus Callosum Fractional Anisotropy Differences in Patients with Cognitive Impairment', Diagnostics, vol. 13, no. 24, 3679. https://doi.org/10.3390/diagnostics132436792075-4418https://dspace.rsu.lv/jspui/handle/123456789/15095Publisher Copyright: © 2023 by the authors.Diffusion tensor imaging (DTI) is an MRI analysis method that could help assess cognitive impairment (CI) in the ageing population more accurately. In this research, we evaluated fractional anisotropy (FA) of whole brain (WB) and corpus callosum (CC) in patients with normal cognition (NC), mild cognitive impairment (MCI), and moderate/severe cognitive impairment (SCI). In total, 41 participants were included in a cross-sectional study and divided into groups based on Montreal Cognitive Assessment (MoCA) scores (NC group, nine participants, MCI group, sixteen participants, and SCI group, sixteen participants). All participants underwent an MRI examination that included a DTI sequence. FA values between the groups were assessed by analysing FA value and age normative percentile. We did not find statistically significant differences between the groups when analysing CC FA values. Both approaches showed statistically significant differences in WB FA values between the MCI-SCI and MCI-NC groups, where the MCI group participants showed the highest mean FA and highest mean FA normative percentile results in WB.1962809enginfo:eu-repo/semantics/openAccessdiffusion tensor imagingMontreal Cognitive Assessmentfractional anisotropycognitive impairmentneuroradiologycognitionmild cognitive impairmentdementia3.2 Clinical medicine1.1. Scientific article indexed in Web of Science and/or Scopus database/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article10.3390/diagnostics13243679http://www.scopus.com/inward/record.url?scp=85180728555&partnerID=8YFLogxK