Brokāns, ArtisDolgopolova, JulijaSaulitis, AgnisSpulle, UldisRancans, KristapsMeiers, DairisHasnere, SigitaBalodis, Arturs2024-10-162024-10-162024-10-14Brokāns, A, Dolgopolova, J, Saulitis, A, Spulle, U, Rancans, K, Meiers, D, Hasnere, S & Balodis, A 2024, 'Optic nerve glioblastoma with optic chiasm involvement : A case report and a brief literature review', Medicina, vol. 60, no. 10, 1687, pp. 1-10. https://doi.org/10.3390/medicina60101687, https://doi.org/10.3390/medicina601016871648-9144https://dspace.rsu.lv/jspui/handle/123456789/16759Publisher Copyright: © 2024 by the authors.Abstract: Background: optic nerve glioblastoma is an uncommon pathology. The optic chiasm, optic tract, or optic nerves are possible places from which the tumor can originate. Most of the neuroimag- ing findings are nonspecific. To confirm the diagnosis, a biopsy is required. A delay to the treatment plan for optic nerve glioblastoma results in poor patient survival rates. Case report: a 68-year-old woman with an uncomplicated medical history presented with exophthalmos, deteriorating eyesight, and partial loss of vision. Using radiological data together with postoperative histopathological and histochemical analysis, optic nerve glioblastoma, IDH-wildtype, with optic chiasm involvement was diagnosed. Conclusion: optic nerve glioblastoma is a rare and aggressive form of cancer that affects the optic nerve, leading to significant vision impairment and potentially life-threatening complications. Treatment options are restricted and difficult because of the location and nature of the condition; surgery, radiation therapy, and chemotherapy are frequently needed as part of a multidisciplinary approach1029422794enginfo:eu-repo/semantics/openAccessoptic nerve glioblastomaNeurosurgeryRadiologyophthalmology3.2 Clinical medicine1.1. Scientific article indexed in Web of Science and/or Scopus databaseGeneral MedicineSDG 3 - Good Health and Well-being/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article10.3390/medicina60101687https://www.mdpi.com/1648-9144/60/10/1687