Please use this identifier to cite or link to this item:
10.3390/M1396
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DC Field | Value | Language |
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dc.contributor.author | Rucins, Martins | - |
dc.contributor.author | Kaukulis, Martins | - |
dc.contributor.author | Plotniece, Aiva | - |
dc.contributor.author | Pajuste, Karlis | - |
dc.contributor.author | Pikun, Nadiia | - |
dc.contributor.author | Sobolev, Arkadij | - |
dc.date.accessioned | 2022-09-02T10:25:01Z | - |
dc.date.available | 2022-09-02T10:25:01Z | - |
dc.date.issued | 2022-09 | - |
dc.identifier.citation | Rucins , M , Kaukulis , M , Plotniece , A , Pajuste , K , Pikun , N & Sobolev , A 2022 , ' 1,1 ′ -{[3,5-Bis(dodecyloxycarbonyl)-4-(naphthalen-2-yl)-1,4-dihydropyridine-2,6-diyl]bis(methylene)}bis{4-[(E)-2-(naphthalen-2-yl)vinyl]pyridin-1-ium}dibromide ' , MolBank , vol. 2022 , no. 3 , M1396 . https://doi.org/10.3390/M1396 | - |
dc.identifier.issn | 1422-8599 | - |
dc.identifier.uri | https://dspace.rsu.lv/jspui/handle/123456789/9511 | - |
dc.description | Funding Information: Funding: This research was funded by the EuroNanoMed3 project TENTACLES No ES RTD/2020/18. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. | - |
dc.description.abstract | Synthesis of a double-charged cationic amphiphilic 1,4-dihydropyridine derivative with dodecyl ester groups at positions 3 and 5 of the 1,4-DHP ring was performed starting from Hantzsch type cyclization of dodecyl acetoacetate, 2-naphthaldehyde and ammonium acetate. Bromination of this compound followed by nucleophilic substitution of bromine with (E)-4-(2-(naphthalen-2-yl)vinyl)pyridine gave the desired cationic amphiphilic 1,1′-{[3,5-bis(dodecyloxycarbonyl)-4-(naph-thalen-2-yl)-1,4-dihydropyridine-2,6-diyl]bis(methylene)}bis{4-[(E)-2-(naphthalen-2-yl)vinyl]pyridin-1-ium}dibromide. The obtained target compound was fully characterized by IR, UV,1 H-NMR,13 C-NMR, HRMS and microanalysis. The characterization of the cationic 1,4-DHP nanoparticles in an aqueous solution was performed by DLS measurements. The obtained results showed that the compound formed nanoparticles with an average diameter of around 300 nm, a PDI value of around 490 and a zeta-potential of around 20 mV for freshly prepared samples. However, after one week of storage at room temperature, an aggregation of nanoparticles was detected. | en |
dc.format.extent | 488154 | - |
dc.language.iso | eng | - |
dc.relation.ispartof | MolBank | - |
dc.rights | info:eu-repo/semantics/openAccess | - |
dc.subject | 1,4-dihydropyridines | - |
dc.subject | DLS | - |
dc.subject | nanoparticles | - |
dc.subject | self-assembling properties | - |
dc.subject | styrylpyridinium dyes | - |
dc.subject | synthetic lipids | - |
dc.subject | 1.4 Chemical sciences | - |
dc.subject | 1.6 Biological sciences | - |
dc.subject | 1.1. Scientific article indexed in Web of Science and/or Scopus database | - |
dc.subject | Biochemistry | - |
dc.subject | Physical and Theoretical Chemistry | - |
dc.subject | Organic Chemistry | - |
dc.title | 1,1′-{[3,5-Bis(dodecyloxycarbonyl)-4-(naphthalen-2-yl)-1,4-dihydropyridine-2,6-diyl]bis(methylene)}bis{4-[(E)-2-(naphthalen-2-yl)vinyl]pyridin-1-ium}dibromide | en |
dc.type | /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article | - |
dc.identifier.doi | 10.3390/M1396 | - |
dc.identifier.url | http://www.scopus.com/inward/record.url?scp=85133329504&partnerID=8YFLogxK | - |
dc.description.status | Peer reviewed | - |
Appears in Collections: | Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure |
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molbank_2022_M1396.pdf | 476.71 kB | Adobe PDF | View/Open |
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