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dc.contributor.authorNora-Krūkle, Zaiga-
dc.contributor.authorRasa, Santa-
dc.contributor.authorVilmane, Anda-
dc.contributor.authorGrāvelsiņa, Sabīne-
dc.contributor.authorKālis, Mārtiņš-
dc.contributor.authorZiemele, Inga-
dc.contributor.authorNaciute, Milda-
dc.contributor.authorPetraitiene, Sigita-
dc.contributor.authorMieliauskaite, Diana-
dc.contributor.authorKlimantaviciene, Migle-
dc.contributor.authorGirkontaite, Irute-
dc.contributor.authorLiu, Hsin Fu-
dc.contributor.authorLin, Jih Hui-
dc.contributor.authorLin, Yung Cheng-
dc.contributor.authorChan, Hsiu Chuan-
dc.contributor.authorGardovska, Dace-
dc.contributor.authorMurovska, Modra-
dc.identifier.citationNora-Krūkle , Z , Rasa , S , Vilmane , A , Grāvelsiņa , S , Kālis , M , Ziemele , I , Naciute , M , Petraitiene , S , Mieliauskaite , D , Klimantaviciene , M , Girkontaite , I , Liu , H F , Lin , J H , Lin , Y C , Chan , H C , Gardovska , D & Murovska , M 2016 , ' Presence of Human Bocavirus 1 in Hospitalised Children with Acute Respiratory Tract Infections in Latvia and Lithuania ' , Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences , vol. 70 , no. 4 , pp. 198-204 .
dc.identifier.otherPURE: 23623037-
dc.identifier.otherPURE UUID: 54c75c9e-0f0c-451e-b52e-4ed3341b54af-
dc.identifier.otherScopus: 84983380490-
dc.descriptionFunding Information: This study was supported by Republic of China (Taiwan)-Republic of Latvia-Republic of Lithuania scientific collaboration project, "Establishing of the framework to track molecular epidemiology of Parvoviruses and to correlate sequence variability with different clinical manifestations" (Research Council of Latvia Nr. gr. 6-25/2012/0026, Research Council of Lithuania TAPLLT02/201) and by project Nr. RSU ZP 17/2013 "Epidemiology, pathogenicity of human Bocavirus (HBoV) species and possible association with lower respiratory tract illnesses and acute gastroenteritis in children". We are grateful to Rita Nikitenkiene and Irina Maksimova for technical help. Publisher Copyright: © 2016 by Zaiga Nora-Krūkle. Copyright: Copyright 2016 Elsevier B.V., All rights reserved.-
dc.description.abstractHuman bocavirus 1 (HBoV1) is a parvovirus recently found to be a possible aetiologic agent of acute respiratory disease in children. We conducted the first clinical and molecular study on this virus in Latvia (LV) and Lithuania (LT). The aim of the study was to determine the occurrence of HBoV1 in respiratory tract samples taken from hospitalised children with acute respiratory tract infections in LV and LT. In total 186 children with age one to 50 months, and who fulfilled criteria of acute respiratory tract infection, including lower respiratory tract infections, with or without fever, were included in this study. A nasopharyngeal aspirate was obtained from each patient on admission. DNA was isolated and polimerase chain reaction (PCR) performed targeting the HBoV1 NS1sequence. HBoV1 positive samples were sequenced and phylogenetic analysis was performed. HBoV1 sequence was detected in 42 (32%) of 130 LV and in 8 (14%) of 56 LT samples. In LV the majority of patients with HBoV1 infection were observed in February while in LT in October. The phylogenetic tree for HBoV1 indicated that isolates of HBoV1 cluster closely and include almost all of the isolates in this study. HBoV1 is common in Latvia and Lithuania and might be a significant pathogen that contributes to acute respiratory tract infections in children.en
dc.relation.ispartofProceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences-
dc.subjectphylogenetic analysis-
dc.subjectrespiratory tract infections-
dc.subject3.3 Health sciences-
dc.subject3.2 Clinical medicine-
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database-
dc.titlePresence of Human Bocavirus 1 in Hospitalised Children with Acute Respiratory Tract Infections in Latvia and Lithuaniaen
dc.contributor.institutionInstitute of Microbiology and Virology-
dc.contributor.institutionRīga Stradiņš University-
dc.description.statusPeer reviewed-
Appears in Collections:Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure

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