Case Series of Multisystem Inflammatory Syndrome (MIS-C) in Children during the SARS-CoV-2 Pandemic in Latvia

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dc.contributor.authorRacko, Iveta
dc.contributor.authorSmane, Liene
dc.contributor.authorKlavina, Lizete
dc.contributor.authorPucuka, Zanda
dc.contributor.authorRoge, Ieva
dc.contributor.authorPavare, Jana
dc.contributor.institutionDepartment of Paediatrics
dc.date.accessioned2021-08-04T08:20:01Z
dc.date.available2021-08-04T08:20:01Z
dc.date.issued2021-06-11
dc.description.abstractThe total number of COVID-19 positive cases in Latvia has escalated rapidly since October 2020, peaking in late December 2020 and early January 2021. Children generally develop COVID-19 more mildly than adults; however, it can be complicated by multisystem inflammatory syndrome in children (MIS-C). This case study aims were to assess demographic characteristics and the underlying medical conditions, and clinical, investigative and treatment data among 13 MIS-C patients using electronic medical records. All 13 had acute illness or contact with someone who was COVID-19 positive two to six weeks before MIS-C onset. Only five of the 13 were symptomatic during the acute COVID-19 phase. The median age was 8.8 years; 11/13 patients were male, 10/13 had been previously healthy, and all 13 patients tested positive for SARS-CoV-2 by RT-PCR or antibody testing. The most commonly involved organ systems were the gastrointestinal (13/13), hematologic (13/13), cardiovascular (13/13), skin and mucosa (13/13), and respiratory (12/13) ones. The median hospital stay was 13 (interquartile range, 11 to 18) days; 7/13 patients received intensive care, 6/13 oxygen support, and 5/13 received inotropic support. No deaths occurred. During the current pandemic, every child with a fever should have a clearly defined epidemiological history of COVID-19, a careful clinical assessment of possible multiple organ-system involvement, with a special focus on children with severe abdominal pain and/or skin and mucocutaneous lesions.en
dc.description.statusPeer reviewed
dc.format.extent11
dc.format.extent2016687
dc.identifier.citationRacko, I, Smane, L, Klavina, L, Pucuka, Z, Roge, I & Pavare, J 2021, 'Case Series of Multisystem Inflammatory Syndrome (MIS-C) in Children during the SARS-CoV-2 Pandemic in Latvia', CLINICS AND PRACTICE, vol. 11, no. 2, pp. 363-373. https://doi.org/10.3390/clinpract11020051
dc.identifier.doi10.3390/clinpract11020051
dc.identifier.issn2039-7275
dc.identifier.otherMendeley: df7dd6bd-4088-3080-a3c3-3f582b69c6dd
dc.identifier.otherunpaywall: 10.3390/clinpract11020051
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/5944
dc.identifier.urlhttps://www.mendeley.com/catalogue/df7dd6bd-4088-3080-a3c3-3f582b69c6dd/
dc.language.isoeng
dc.relation.ispartofCLINICS AND PRACTICE
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCOVID-19
dc.subjectSARS-CoV-2
dc.subjectmultisystem inflammatory syndrome in children (MIS-C)
dc.subject3.2 Clinical medicine
dc.subject1.6 Biological sciences
dc.subject3.3 Health sciences
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.titleCase Series of Multisystem Inflammatory Syndrome (MIS-C) in Children during the SARS-CoV-2 Pandemic in Latviaen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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