CORRELATION OF INTESTINAL ULTRASOUND DATA WITH LABORATORY MARKERS OF INFLAMMATION FOR PATIENTS WITH INFLAMMATORY BOWEL DISEASE

Simple item page
dc.contributor.authorJevdokimova, Natālija
dc.contributor.authorJevdokimov, Denis
dc.contributor.authorTeterina, Irena
dc.contributor.authorPokrotnieks, Juris
dc.contributor.authorPuķītis, Aldis
dc.contributor.authorMokricka, Viktorija
dc.contributor.institutionFaculty of Pharmacy
dc.contributor.institutionFaculty of Medicine
dc.date.accessioned2024-09-24T10:50:01Z
dc.date.available2024-09-24T10:50:01Z
dc.date.issued2024-08
dc.descriptionPublisher Copyright: © The Authors.
dc.description.abstractIntestinal ultrasound is a new non-invasive imaging method that can be used for diagnostics of inflammatory bowel disease, to evaluate the response to therapy, and monitor serious complications of the disease in time. A prospective study was performed in Pauls Stradiņš Clinical University Hospital. Thirty patients were enrolled in the study: 21 patients with ulcerative colitis and 9 patients with Crohn’s disease. Intestinal ultrasound was performed using Diagnostic Ultrasound System Arietta S70 (Hitachi, Japan). Intestinal wall structure (thickness), blood flow (Limberg score), intraluminal content, mesenteric fat hypertrophy and lymph nodes were evaluated, and laboratory markers of inflammation and clinical activity indices were analysed. Increased bowel wall thickness (BWT) (3 3 mm) was detected in 22 patients (73.3%), and wall stratification in 17 patients (56.7%). Using statistical analysis, it was concluded that there was a positive and statistically significant correlation between bowel wall thickness and ferritin (r = 0.60; p < 0.001), CRP (r = 0.49, p = 0.006), and faecal calprotectin (r = 0.84, p < 0.001). Intestinal ultrasound is a promising real time monitoring method for both Crohn’s disease and ulcerative colitis, which showed statistically significant correlations between bowel wall thickness, bowel wall stratification, blood flow, laboratory markers of inflammation and clinical activity indices.en
dc.description.statusPeer reviewed
dc.format.extent8
dc.format.extent771072
dc.identifier.citationJevdokimova, N, Jevdokimov, D, Teterina, I, Pokrotnieks, J, Puķītis, A & Mokricka, V 2024, 'CORRELATION OF INTESTINAL ULTRASOUND DATA WITH LABORATORY MARKERS OF INFLAMMATION FOR PATIENTS WITH INFLAMMATORY BOWEL DISEASE', Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences, vol. 78, no. 4, pp. 290-297. https://doi.org/10.2478/prolas-2024-0040
dc.identifier.doi10.2478/prolas-2024-0040
dc.identifier.issn1407-009X
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/16708
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85204056960&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofProceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectIBD activity score
dc.subjectinflammatory bowel disease
dc.subjectintestinal ultrasound
dc.subjectMilan ultrasound criteria
dc.subjectSUS-CD score
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectGeneral
dc.titleCORRELATION OF INTESTINAL ULTRASOUND DATA WITH LABORATORY MARKERS OF INFLAMMATION FOR PATIENTS WITH INFLAMMATORY BOWEL DISEASEen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
CORRELATION_OF_INTESTINAL_ULTRASOUND_DATA_WITH_LABORATORY_MARKERS.pdf
Size:
753 KB
Format:
Adobe Portable Document Format
Download

Collections

Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure