Antidiabetic Properties of the Root Extracts of Dandelion (Taraxacum officinale) and Burdock (Arctium lappa)

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dc.contributor.authorZolotova, Daria
dc.contributor.authorTeterovska, Renāte
dc.contributor.authorBandere, Dace
dc.contributor.authorLauberte, Līga
dc.contributor.authorNiedra, Santa
dc.contributor.institutionDepartment of Pharmaceutical Chemistry
dc.contributor.institutionRed Cross Medical College of Rīga Stradiņš University
dc.contributor.institutionLaboratory of Finished Dosage Forms
dc.date.accessioned2024-04-05T07:45:01Z
dc.date.available2024-04-05T07:45:01Z
dc.date.issued2024-04-03
dc.descriptionPublisher Copyright: © 2024 by the authors.
dc.description.abstractSeveral preclinical studies suggest the potential of edible plants in controlling blood sugar levels and stabilizing diet. The goals of the study were to examine, analyze, and describe whether there are chemical compounds in dandelion and burdock roots that could have antidiabetic properties. The 70% ethyl alcohol and lyophilizate extracts (AE and LE, respectively), were used, and analyses were carried out on their total polysaccharide (TP), total phenolic content (TPC), tannin, and inulin. The antioxidant activity of extracts was determined using the DPPH (2,2-diphenyl-1-picrylhydrazyl) assay, and hypoglycemic properties were based on α-amylase activity. Liquid chromatography–mass spectrometry was used for the tentative identification of the chemical components. Qualitative techniques confirmed the presence of inulin in both roots. Analysis of TPC, tannin content, DPPH assay, and α-amylase activity revealed higher values for burdock compared to dandelion. However, dandelion exhibited higher TP content. Burdock contained a small amount of tannin, whereas the tannin content in dandelion was insignificant. All LE consistently exhibited higher values in all analyses and assays for all roots compared to AE. Despite burdock root showing overall better results, it is uncertain whether these plants can be recommended as antidiabetic agents without in vivo studies.en
dc.description.statusPeer reviewed
dc.format.extent1630508
dc.identifier.citationZolotova, D, Teterovska, R, Bandere, D, Lauberte, L & Niedra, S 2024, 'Antidiabetic Properties of the Root Extracts of Dandelion (Taraxacum officinale) and Burdock (Arctium lappa)', Plants, vol. 13, no. 7, 1021. https://doi.org/10.3390/plants13071021
dc.identifier.doi10.3390/plants13071021
dc.identifier.issn2223-7747
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/15419
dc.identifier.urlhttps://www.mdpi.com/2223-7747/13/7/1021
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85190141235&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofPlants
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectdiabetes mellitus
dc.subjectdandelion
dc.subjectburdock
dc.subjecttannin
dc.subjectinulin
dc.subjecttotal polysaccaride
dc.subjecttotal phenolic content
dc.subjectantioxidant
dc.subjecthypoglycemic properties
dc.subject3.1 Basic medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.titleAntidiabetic Properties of the Root Extracts of Dandelion (Taraxacum officinale) and Burdock (Arctium lappa)en
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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