Functional Disability and Brain MRI Volumetry Results among Multiple Sclerosis Patients during 5-Year Follow-Up
No Thumbnail Available
Date
2023-06-04
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Background and Objectives: We aimed to determine the link between brain volumetry results and functional disability calculated using the Expanded Disability Status Scale (EDSS) among multiple sclerosis (MS) patients in relation to the provided treatment (disease-modifying therapies (DMTs)) during a 5-year follow-up period. Materials and Methods: A retrospective cohort study was performed enrolling 66 consecutive patients with a confirmed diagnosis of MS, predominantly females (62% (n = 41)). Relapsing–remitting (RR) MS was noted in 92% (n = 61) of patients, with the rest being patients with secondary progressive (SP) MS. The mean age was 43.3 years (SD 8.3 years).
Description
Funding Information: This research was funded by the Pauls Stradins Clinical University Hospital Scientific Institute Research Grant. Publisher Copyright: © 2023 by the authors.
Keywords
multiple sclerosis, brain atrophy, MRI, EDSS, disability, 3.2 Clinical medicine, 1.1. Scientific article indexed in Web of Science and/or Scopus database
Citation
Strautmane, S, Balodis, A, Teivāne, A, Grabovska, D, Naudiņš, E, Urbanovics, D, Fišermans, E, Mednieks, J, Flintere-Flinta, A, Priede, Z, Millers, A & Zolovs, M 2023, 'Functional Disability and Brain MRI Volumetry Results among Multiple Sclerosis Patients during 5-Year Follow-Up', Medicina, vol. 59, no. 6, 1082. https://doi.org/10.3390/medicina59061082