Establishing the cut-offs of leaky gut syndrome diagnostic : where are we now?

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dc.contributor.authorRodina, Jekaterina
dc.contributor.authorDerovs, Aleksejs
dc.contributor.institutionDepartment of Internal Diseases
dc.contributor.institutionDepartment of Infectology
dc.date.accessioned2023-01-16T08:35:01Z
dc.date.available2023-01-16T08:35:01Z
dc.date.issued2022-12
dc.descriptionPublisher Copyright: © 2022 Jekaterina Rodina et al., published by Sciendo.
dc.description.abstractGastrointestinal mucosa forms a surface that interacts with many external factors. Beside the digestion and absorption of nutrients, it also acts as a barrier to allergens, pathogens, and toxins. Leaky gut syndrome is defined as a gut mucosal barrier dysfunction, which results in abnormally increased intestinal permeability. Research shows that leaky gut syndrome (LGS) has a pathogenetic relationship with a series of gastrointestinal and extra-intestinal disorders. This review discusses the current understanding of intestinal barrier composition and pathological contribution of LGS to various diseases. The major aim of this paper is to review different methods for diagnostics and evaluation of intestinal wall permeability, identifying their priorities and disadvantages.en
dc.description.statusPeer reviewed
dc.format.extent9
dc.format.extent131182
dc.identifier.citationRodina, J & Derovs, A 2022, 'Establishing the cut-offs of leaky gut syndrome diagnostic : where are we now?', Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences., vol. 76, no. 5/6, pp. 569-577. https://doi.org/10.2478/prolas-2022-0089
dc.identifier.doi10.2478/prolas-2022-0089
dc.identifier.issn1407-009X
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/10082
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85144261337&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofProceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences.
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectgut permeability
dc.subjectintestinal barrier
dc.subjectleaky gut
dc.subjectmicrobiota
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectGeneral
dc.titleEstablishing the cut-offs of leaky gut syndrome diagnostic : where are we now?en
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/systematicreview

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